Search

Your search keyword '"antipsychotic agents/adverse effects"' showing total 2 results
Start Over Descriptor "antipsychotic agents/adverse effects" Journal asia-pacific psychiatry
2 results on '"antipsychotic agents/adverse effects"'

1. The effectiveness and safety of amisulpride in Chinese patients with schizophrenia: An 8-week, prospective, open-label, multicenter, single-arm study.

Author

Liang, Ying, Cao, Changan, Zhu, Cheng, Wang, Chuanyue, Zhang, Congpei, Dong, Fang, Yang, Fude, Deng, Hong, Yu, Jingjie, Tang, Jisheng, Su, Lei, Xin, Limin, Hong, Ling, Gao, Minglong, Tang, Muni, Xie, Shiping, Lu, Shuiping, Liu, Tiebang, Xu, Xiaojin, and Wang, Xijin

Subjects
*AMISULPRIDE, *DRUG efficacy, *DRUG side effects, *ANTIPSYCHOTIC agents, *PEOPLE with schizophrenia
Abstract

Introduction This study evaluated the effectiveness and safety of amisulpride in Chinese schizophrenia patients. Methods A multicenter, single-arm Phase IV study (NCT01795183). Chinese patients with schizophrenia received amisulpride for 8 weeks. The primary endpoint was ≥50% decrease in Positive and Negative Syndrome Scale total score from Baseline to Week 8. Results A total of 316 patients were enrolled; 295 were included in the effectiveness analysis; 66.8% (197/295) achieved ≥50% decrease in Positive and Negative Syndrome Scale total score from Baseline to Week 8. Nine patients discontinued treatment because of adverse events. Discussion Amisulpride had clinical effectiveness and was relatively well tolerated in Chinese patients with schizophrenia. [ABSTRACT FROM AUTHOR]

Published
2016
Full Text
View/download PDF

2. The effectiveness and safety of amisulpride in Chinese patients with schizophrenia: An 8‐week, prospective, open‐label, multicenter, single‐arm study

Author

Lei Su, Zhiyu Chen, F. Yang, Xijin Wang, Jisheng Tang, Shi-Ping Xie, Xin Yu, Tiebang Liu, Xuanzi Li, Ying Liang, Fang Dong, Xueyi Wang, Hong Deng, Li-Min Xin, Ling Hong, Muni Tang, Yong Zhang, Yi Li, Chuanyue Wang, Xiaojin Xu, Changan Cao, Congpei Zhang, Shuiping Lu, Cheng Zhu, Minglong Gao, and Jingjie Yu

Subjects
Adult, Male, medicine.medical_specialty, Adolescent, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, mental disorders, medicine, Clinical endpoint, Humans, antipsychotic agents/adverse effects, Prospective Studies, Amisulpride, Young adult, Adverse effect, Prospective cohort study, Psychiatry, antipsychotic agents/therapeutic use, Chinese, Positive and Negative Syndrome Scale, Brief Report, General Medicine, Middle Aged, medicine.disease, 030227 psychiatry, Psychiatry and Mental health, Treatment Outcome, amisulpride, Schizophrenia, Female, Brief Reports, Sulpiride, Psychology, 030217 neurology & neurosurgery, Antipsychotic Agents, medicine.drug
Abstract

Introduction This study evaluated the effectiveness and safety of amisulpride in Chinese schizophrenia patients. Methods A multicenter, single-arm Phase IV study (NCT01795183). Chinese patients with schizophrenia received amisulpride for 8 weeks. The primary endpoint was ≥50% decrease in Positive and Negative Syndrome Scale total score from Baseline to Week 8. Results A total of 316 patients were enrolled; 295 were included in the effectiveness analysis; 66.8% (197/295) achieved ≥50% decrease in Positive and Negative Syndrome Scale total score from Baseline to Week 8. Nine patients discontinued treatment because of adverse events. Discussion Amisulpride had clinical effectiveness and was relatively well tolerated in Chinese patients with schizophrenia.

Published
2016

Catalog

Books, media, physical & digital resources
See catalog results