1. Primary Total Hip Arthroplasty in Patients With Ehlers-Danlos Syndrome: A Retrospective Matched-Cohort Study
- Author
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Benjamin K. Wilke, Michael J. Taunton, Glenn G. Shi, Michael G. Heckman, Christian P. Guier, and Cameron K. Ledford
- Subjects
musculoskeletal diseases ,medicine.medical_specialty ,Complications ,Population ,Osteoarthritis ,Joint laxity ,03 medical and health sciences ,0302 clinical medicine ,Matched cohort ,lcsh:Orthopedic surgery ,Medicine ,Dislocation ,Orthopedics and Sports Medicine ,Revision rate ,In patient ,030212 general & internal medicine ,education ,Original Research ,030222 orthopedics ,education.field_of_study ,business.industry ,medicine.disease ,Connective tissue disorder ,Surgery ,lcsh:RD701-811 ,Ehlers–Danlos syndrome ,Total hip arthroplasty ,business ,Ehlers-Danlos syndrome - Abstract
Background Ehlers-Danlos syndromes (EDSs) are connective-tissue disorders resulting in joint laxity. Soft-tissue stability is a concern in these patients when they undergo total hip arthroplasty (THA). Our purpose was to compare THAs in the population with EDS with a matched control undergoing THA for osteoarthritis. Methods Thirteen patients with EDS underwent THA from 1997 to 2017. Matching was 1:3 with a control group of patients who underwent THA for osteoarthritis. Matching was based on the gender, age, and length of follow-up. Results We found no difference in demographics or postoperative Harris Hip Scores between the cohorts (P > .05). Two patients (15.4%) with EDS and 2 patients (5.1%) in the control group suffered a dislocation. We found no difference in the reoperation or revision rate between the groups (P = .28). Conclusions Patients with EDS have a significant improvement in postoperative Harris Hip Scores after THA. These patients also have a high dislocation rate after surgery, and alternative approaches and technologies such as dual-mobility components should be considered to reduce the rate of dislocation in this population.
- Published
- 2020