1. NON-ADHERENCE TO HEPATITIS C TREATMENT: A BRAZILIAN REPORT
- Author
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Claudia Alexandra Pontes IVANTES, Bernardo Carvalho da SILVA, Gabriel Gonçalves ACOSTA, Fabiane Beatriz Neves El TAWIL, and Renato NISIHARA
- Subjects
Male ,Coinfection ,cooperação do paciente ,Gastroenterology ,HIV Infections ,agentes antivirais ,Hepacivirus ,RC799-869 ,Hepatitis C, Chronic ,Diseases of the digestive system. Gastroenterology ,Hepatitis C ,patient compliance ,Treatment Outcome ,Hepatite C ,antiviral agents ,Humans ,Female ,Brazil ,Retrospective Studies - Abstract
BACKGROUND: In Brazil, since 2015, the treatment of hepatitis C is provided by SUS (Public Health System) with direct-acting antiviral (DAA). OBJECTIVE: To describe the rate of non-adherence patients to hepatitis C treatment by DAA, investigating the epidemiological data in a large database from Curitiba, Brazil. METHODS: Retrospective study with patients treated between January 2015 and June 2019. Patients were considered adherent when received all medication doses during their treatment. The following data were evaluated: gender, age, type of treatment, period of treatment, presence of diabetes or HIV, previous therapy, originated from SUS or private medicine, fibrosis grade and HCV genotype. RESULTS: 1248 patients (56.8% males) were studied and 102/1248 (8.2%) were non-adherent to treatment. Age or gender not influenced significantly; 10.2% patients from SUS and 3.7% individuals from private medicine were non-adherent (P
- Published
- 2021