1. [Evaluation of clinical, laboratorial and ultrasonographic predicting factors of malignancy in thyroid nodules]
- Author
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Ana Luiza Silva, Rio, Rosa Paula Mello, Biscolla, Danielle Macellaro, Andreoni, Cléber Pinto, Camacho, Cláudia Cristina Doimo, Nakabashi, Maria da Conceição de Oliveira Carneiro, Mamone, Elza Setsuku, Ikejiri, Luiza K, Matsumura, Jairo Tabacow, Hidal, Rui Monteiro de Barros, Maciel, and Reinaldo Perrone, Furlanetto
- Subjects
Adult ,Aged, 80 and over ,Male ,Adolescent ,Biopsy, Fine-Needle ,Carcinoma ,Thyroid Gland ,Calcinosis ,Middle Aged ,Young Adult ,Humans ,Female ,Thyroid Neoplasms ,Thyroid Nodule ,Child ,Epidemiologic Methods ,Aged ,Ultrasonography - Abstract
To evaluate the risk of malignancy in thyroid nodules through clinical, laboratory, ultrasonographic and cytological aspects.741 nodules of 407 patients.The cytology was benign (60,5%), indeterminate (23,3%), malignant (8,3%) or nondiagnostic (7,6%). The prevalence of cancer in indeterminate citology was 18,5% (16% in follicular lesions, 44% in suspicious). The diagnosis of malignancy was 17,2% (n = 70). The frequency of cancer in women (15,2%) was lower than in men (27,9%). There was an inverse relation between age and cancer risk. There was no statistical significance in the prevalence of cancer according to number, size of nodules or TSH levels. Hypoechogenicity and microcalcifications on ultrasound were risk factors.The risk of malignancy was higher in men, hypoechoic nodules, with microcalcifications and was inversely related to age. The TSH level was not an independent factor predictive of malignancy.
- Published
- 2010