1. [Endogenous hyperinsulinism: two diagnostic challenges].
- Author
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Gonçalves AP, Baptista F, Nobre E, and Carmo Id
- Subjects
- C-Peptide blood, Female, Humans, Insulin blood, Male, Middle Aged, Pancreas diagnostic imaging, Pancreas pathology, Proinsulin blood, Ultrasonography, Hyperinsulinism etiology, Hypoglycemia etiology, Insulinoma complications, Multiple Myeloma complications, Pancreatic Neoplasms complications
- Abstract
Hypoglycemia in apparently healthy adults is a rare finding in clinical practice requiring a thorough investigation of the cause. During the investigation, identification of hypoglycemia associated with inappropriately high levels of insulin and C-peptide should prompt the exclusion of rare causes of hypoglycemia, including pancreatic islet-cells disease and autoimmune hypoglycemia. In this paper, we describe two cases of hypoglycemia associated with endogenous hyperinsulinism, whose causes are uncommon in clinical practice, and review important aspects of the diagnosis and treatment of hyperinsulinemic hypoglycemia.
- Published
- 2014
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