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1. Association between HLA class I antigens and response to interferon therapy in children with chronic HBV hepatitis.

Author

Giacchino R, Nocera A, Timitilli A, Cristina E, Giambartolomei G, Caocci F, Cirillo C, and Barocci S

Subjects
Alleles, Child, Hepatitis B immunology, Hepatitis, Chronic immunology, Humans, Genes, MHC Class I, HLA-B35 Antigen analysis, Hepatitis B therapy, Hepatitis, Chronic therapy, Interferon-alpha therapeutic use
Abstract

In this preliminary study, children with chronic HBV hepatitis, as was also previously shown for adults, respond to interferon therapy in an HLA class I antigen dependent manner. If this can be confirmed on a large scale, HLA typing may serve as a useful indication of interferon-therapy responders.

Published
1992
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