1. The identification and characterization of novel rat hepatitis E virus strains in Bali and Sumbawa, Indonesia.
- Author
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Primadharsini, Putu Prathiwi, Mulyanto, Wibawa, I. Dewa Nyoman, Anggoro, Joko, Nishizawa, Tsutomu, Takahashi, Masaharu, Jirintai, Suljid, and Okamoto, Hiroaki
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VIRUS identification , *HEPATITIS E virus , *VIRAL genetics , *VIRUS diversity - Abstract
All three genetic groups of ratHEV have been found in Indonesia, suggesting the presence of additional variants of ratHEV in unexamined areas of Indonesia. A total of 242 wild rats were captured in Bali and Sumbawa, Indonesia, during 2014-2016. Among them, 4.1% were seropositive for anti-ratHEV IgG and two (0.8%) had detectable ratHEV RNA: ratESUMBAWA-140L and ratEBali2016D-047L, sharing 84.9-85.4% and 86.9-92.1% nucleotide identity with the reported G2 strains, respectively. The provisional criteria supported the notion that the ratEBali2016D-047L and ratESUMBAWA-140L strains were novel G2 variants. These results suggested the spatial distribution of further divergent ratHEV strains in Indonesia. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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