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The Prenatal Diagnosis of Hereditary Disorders by Dr. Aubrey Milunsky was expressly written for physicians, counselors, and other medical personnel who are in a position to counsel families at risk for a variety of genetic disorders. The content of the book is more general than that suggested by the title. The author has had extensive experience with intrauterine diagnosis since the late 1960s and reviews his experience, as well as that of others, relating to prenatal diagnosis. In addition, sections on genetic counseling, genetics and society, and morality, ethics, law, and the future are included. The text is, in general, easy to read, highly accurate, and provides an excellent review of the field up to the time that it was written. The data on amniocentesis are accurate and the experience is reviewed in great detail. The entire text is easily understandable and certainly answers the overwhelming majority of questions

In the ten chapters selected topics of developmental biochemistry are presented by 14 well chosen authors. Sereni and Principi tackled the complicated question of how perinatal liver function is regulated; the authors collected valuable information on this relatively new and little explored topic. A very impressive achievement in intrauterine diagnosis and antenatal detection of inherited diseases is presented by Nyhan who excellently surveys the great number of biochemical disorders with didactic skill. The complicated and complex regulation of genetic expression is described by Benson. This author who also edited the book discusses the ten principal factors involved in protein synthesis, the programmed differential expression of the genome, and the biosynthesis and control of RNA and protein. Walker surveys the development of enzymes for carbohydrate metabolism; he stresses the importance of control mechanisms and rate-controlling enzymes in the perinatal period. The developmental aspects of lipid metabolism are described by Myatt; the