1. Ceftazidime-Related Nonconvulsive Status Epilepticus
- Author
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Amy D. Klion, Jeffrey Kallsen, William M. Nauseef, and Clayton T. Cowl
- Subjects
medicine.medical_specialty ,Pediatrics ,business.industry ,medicine.drug_class ,Encephalopathy ,Cephalosporin ,Ceftazidime ,Status epilepticus ,medicine.disease ,Epilepsy ,Internal Medicine ,medicine ,medicine.symptom ,business ,Intensive care medicine ,Adverse effect ,Myoclonus ,Meningitis ,medicine.drug - Abstract
The third-generation cephalosporin, ceftazidime, is widely used for the treatment of serious gram-negative infections. As is true of cephalosporins in general, reported adverse effects have been few. We report a case of ceftazidime-induced status epilepticus in a patient with Pseudomonas aeruginosa meningitis and compare the clinical manifestations of this case with those of two previously described cases of ceftazidime-related encephalopathy. This diagnosis should be entertained and an electroencephalogram should be obtained in all patients with myoclonus and/or altered mental status while they are receiving ceftazidime therapy.
- Published
- 1994