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Your search keyword '"Abinun, M."' showing total 15 results
Start Over Author "Abinun, M." Journal archives of disease in childhood
15 results on '"Abinun, M."'

1. Autologous heamatopoietic stem cell transplantation in juvenile idiopathic arthritis: a powerful strategy when other treatments have failed. (Rheumatology)

Author

Wedderburn, L.R., Abinun, M., Palmer, P., and Foster, H.E.

Subjects
Juvenile arthritis -- Care and treatment, Hematopoietic stem cells -- Transplantation, Family and marriage, Health, Care and treatment, Usage
Abstract

Despite modern therapies, juvenile idiopathic arthritis (JIA) remains a significant cause of morbidity in children. The long term outcome of JIA is variable. Thus, while the prognosis for many children [...]

Published
2003

2. Antibody deficiency and autoimmunity in 22q 11.2 deletion syndrome. (Original Article)

Author

Gennery, A.R., Barge, D., O'Sullivan, J.J., Flood, T.J., Abinun, M., and Cant, A.J.

Subjects
Immunological deficiency syndromes -- Genetic aspects, Autoimmunity -- Genetic aspects -- Physiological aspects, Chromosome deletion -- Physiological aspects -- Genetic aspects, Human chromosomes -- Physiological aspects, Family and marriage, Health, Physiological aspects, Genetic aspects
Abstract

Background: Although severe T cell immunodeficiency in DiGeorge anomaly is rare, previous studies of humoral function in these patients have found no antibody abnormalities but have not examined the response [...]

Published
2002

11. Monitoring of long term oral steroid use in children

Author

Khawaja, K., Abinun, M., Friswell, M., and Foster, H.

Subjects
Osteoporosis -- Care and treatment -- Research, Steroids (Drugs) -- Health aspects -- Research, Children -- Health aspects -- Research, Family and marriage, Health, Care and treatment, Research, Health aspects
Abstract

Aim: Long term steroids have a wide range of undesirable side effects and assessment of these varies widely. We wished to examine how children are currently monitored and to use [...]

Published
2004

12. Does the process of care affect early outcome of juvenile arthritis (JIA)?

Author

Eltringham, M.S., Myers, A., Proctor, S.J., Taylor, P., Parker, L., Abinun, M., Friswell, M., Kay, L.J., and Foster, H.E.

Subjects
Children -- Health aspects -- Research, Arthritis -- Care and treatment -- Research, Family and marriage, Health, Care and treatment, Research, Health aspects
Abstract

Aim: The trend to earlier and more aggressive treatment for JIA is based on emerging evidence that this improves outcome. It is recommended that all patients be managed by a [...]

Published
2004

14. Unsuspected Pneumocystis carinii pneumonia at presentation of severe primary immunodeficiency.

Author

Berrington, Janet E., Flood, Terence J., Abinun, Mario, Galloway, Angela, Cant, Andrew J., Berrington, J E, Flood, T J, Abinun, M, Galloway, A, and Cant, A J

Abstract

Background: Pneumocystis carinii is an important pathogen in immunodeficiency but may be an unrecognised cause of respiratory compromise.Objectives: To ascertain the incidence of P carinii pneumonia (PCP) at presentation of severe combined immunodeficiency (SCID), whether it had been diagnosed, and the effect of treatment on outcome.Setting: The supraregional paediatric bone marrow transplant unit for primary immunodeficiencies at Newcastle General Hospital.Methods: Retrospective case note review of infants referred with a diagnosis of SCID from 1992 to 1998.Results: Ten of 50 infants had PCP at presentation; only one was diagnosed before transfer. Eight were diagnosed by bronchoalveolar lavage and two by lung biopsy. In only one was P carinii identified in nasopharyngeal secretions. Five required ventilation for respiratory failure but all were successfully treated with co-trimoxazole and methylprednisolone with or without nebulised budesonide. Nine survived to bone marrow transplantation and four are long term survivors after bone marrow transplantation; no deaths were related to PCP.Conclusions: PCP is a common presenting feature of SCID but is rarely recognised. Bronchoalveolar lavage or lung biopsy are needed for diagnosis. Treatment with co-trimoxazole is highly successful. [ABSTRACT FROM AUTHOR]

Published
2000
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15. Severe combined immunodeficiency syndrome presenting with disseminated BCG infection.

Author

Fitzpatrick P, Leonard J, Twomey E, Malone A, Nademi Z, Jackson M, Abinun M, Leahy TR, and Gavin PJ

Subjects
BCG Vaccine adverse effects, Humans, Infant, Male, Opportunistic Infections diagnosis, Opportunistic Infections etiology, Severe Combined Immunodeficiency diagnosis, Tuberculosis diagnosis, Tuberculosis etiology, Mycobacterium bovis, Opportunistic Infections complications, Severe Combined Immunodeficiency complications, Tuberculosis complications
Published
2015
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