1. Nitric oxide attachment to SPIONs: Demonstration of the covalent S NO bond in a nanodelivery system
- Author
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D. Deschênes, Sophie Laurent, Dimitri Stanicki, Edward Sacher, L'h. Yahia, and Laura Karina Mireles
- Subjects
General Physics and Astronomy ,Nanoparticle ,02 engineering and technology ,Surfaces and Interfaces ,General Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Photochemistry ,01 natural sciences ,0104 chemical sciences ,Surfaces, Coatings and Films ,Nitric oxide ,chemistry.chemical_compound ,X-ray photoelectron spectroscopy ,chemistry ,Dimercaptosuccinic acid ,Covalent bond ,Nitrosation ,medicine ,Surface modification ,0210 nano-technology ,Magnetite ,medicine.drug - Abstract
We demonstrate the successful functionalization of magnetite (Fe3O4) nanoparticles, using PEGdithiol and dimercaptosuccinic acid (DMSA). Following functionalization, TEM images show increased sizes, due to the presence of well-defined polymeric coatings. On subsequent nitrosation, X-ray photoelectron spectroscopy (XPS) and time-of-flight secondary ion mass spectroscopy (TOF-SIMS) show the presence of S NO bonds.
- Published
- 2020
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