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This study aimed to evaluate the depth of cure (DoC) of bulk-fill composite resins, measured by the bottom-to-top Vickers microhardness ratio, using different light-curing units (LCUs): single-wave LED, polywave LED, and halogen. Six bulk-fill composites—Tetric EvoCeram Bulk Fill, X-tra base, SonicFill, Venus Bulk Fill, SDR, and Filtek Bulk Fill—were tested. Four LCUs, including one halogen (Elipar Trilight) and three LEDs (Demi Ultra, Valo, and Bluephase style), were employed for polymerization. Vickers hardness measurements were taken at depths of 1 mm to 5 mm. One- and two-way ANOVA (α = 0.05) were used for data analysis. The results revealed significant differences in microhardness and microhardness ratios among the composites at depths of 4 mm and beyond, depending on the LCU used. It was observed that most bulk-fill composites showed an adequate DoC up to 4 mm, but the effectiveness varied with different LCUs. Importantly, polywave LED LCUs did not exhibit a superior advantage in achieving depth of cure compared to monowave LED LCUs for composites containing multiple photoinitiators. These findings suggest that while several factors affect the DoC, the type of LCU plays a crucial role, and polywave LEDs may not offer additional benefits over monowave LEDs.

This study compares dosimetric outcomes of high-dose-rate (HDR) interventional radiotherapy (IRT) using Iridium-192, Volumetric Modulated Arc Therapy (VMAT), and electron beam therapy for non-melanoma skin cancer (NMSC). A retrospective analysis of 25 patients showed that IRT provided a significantly higher mean dose to the clinical target volume (CTV) compared to VMAT and electron beam therapy. IRT and VMAT had comparable V95%CTV coverage, whilst electron therapy was less feasible for large CTVs. IRT delivered higher surface doses while minimizing deep tissue exposure compared to partial arc VMAT. Our findings support IRT for personalized and effective NMSC treatment.

It has been demonstrated that mesenchymal stromal cells (MSCs) act by releasing bioactive molecules, among these are extracellular vesicles (EVs). The MSC-EVs are considered a convenient alternative to cell therapy, showing several functional characteristics of their origin cells. EVs can be collected from conditioned in vitro cultured MSCs. Different processes have been developed to induce in vitro EV release, and these approaches have been demonstrated to also influence MSC potentialities. This study aimed to investigate the effect of serum starvation on MSC characteristics. The morphology, phenotype, differentiation capacity, immunomodulatory ability, and metabolic state were maintained by MSCs cultured under starvation. To evaluate basic ultrastructural characteristics of cells and EVs, Transmission Electron Microscopy (TEM) analysis was performed on MSCs after 12, 24, and 48 h starvation, demonstrating that 24 h starvation was the best time for MSC structure preservation. Further studies are needed to support the hypothesis that MSCs after starvation could still be considered as therapeutic agents.

The primary aim of this study was to provide a sustainable and systemic solution to the prevalent time management challenges within healthcare academia. The secondary aim was to explore the correlations between various factors influencing time management in a dental university setting. To achieve these objectives, a predictive model, the Timebooster Academic Systemic Model (TASM), was developed. This model was crafted through systemic analysis software and a systemic management approach, utilizing three fundamental pillars: teaching, research, and administrative tasks. Soft skill cultivation, automation implementation, the delegation of administrative responsibilities, and the role of resilient academic manager–leaders were also examined. The study found that prioritizing administrative tasks often consumes valuable academic time, resulting in excessive costs and lowered resilience levels among academicians. TASM proposes solutions such as soft skill cultivation, full automation, delegation, and the mitigation of time-consuming elements, emphasizing the role of resilient academic manager–leaders in enhancing collaboration and teamwork. Time management challenges significantly impact academic well-being and resilience. In conclusion, systemic models like TASM provide a valuable framework to address prioritization concerns, identify administrative obstacles, and manage low-value time-consuming tasks within academia in a systemic manner.

According to the World Health Organization (WHO), “a healthy diet is essential for good health and nutrition [...]

Nanophotonics, at the forefront of science and engineering, intrigues researchers across disciplines with its transformative potential for diverse technologies [...]

Basketball is a sport where shooting is one of the most important factors that determines the success or failure of the teams. Therefore, basketball players need to shoot the ball accurately. The present study aimed to evaluate whether different shooting conditions influence the visual behavior of athletes. For this, the Tobbi Pro Glasses 3 equipment was used to evaluate the time of the first fixation, the number of fixations, and the total time of fixations in the basket, during the shooting movement. Different distances to the basket, simulated gym audience noise, and shooting with opposition were considered. A group of 18 athletes with an average age of 22 ± 3.72 years and an average basketball practice experience of 12.5 ± 4.52 years performed 10 valid shots from different distances and different shooting angles, with different restrictions, namely, shooting with simulated opposition and gym audience noise. Statistically significant differences between shooting with opposition and baseline, in terms of the number of fixations and the total time of fixation, were found. Regarding shooting with gym audience noise, differences only occur for the total time of fixations in one position. Despite this, in all variables and positions, the values were lower in shooting with constraints compared to the baseline.

In the area of dental healthcare services, where patients and professionals deal with multiple auditory stimuli, this cross-sectional study reports on the various dynamics of sound preferences, noise obstacles, and the profound impact of music on anxiety reduction within dental office settings. The sample comprises 134 dental patients, primarily females (56.7%), with varying age groups, education levels, and therapy durations in the university clinics of the Department of Dentistry, National and Kapodistrian University of Athens, and four private dental offices at the metropolitan area of Athens, Greece. Notably, 92.5% of the participants reported no hearing loss, and 56.7% exhibited some level of noise sensitivity. This study reveals a moderate to good perceived health status (M = 3.84, SD = 0.95) among participants, with low perceived noise disturbance in university dental clinics. Preferences for instrumental music, foreign pop, and classical music are prominent during waiting times. Potential irritations include impersonal treatment (44%) and staff behavior (41.8%). Correlations and predictors indicate associations between age, gender, educational status, music preferences, and noise disturbances. Findings aim to optimize eco-soundscapes in dental offices, contributing to enhanced patient well-being. The research underscores the potential of music interventions to alleviate dental anxiety and improve the overall dental experience and quality care.

In the face of 21st-century environmental challenges, including climate change, migration pressures, and waste disposal issues, certain healthcare sectors, notably dentistry, pose a significant global environmental footprint with concerns about carbon emissions and waste production. This scoping review searches the paradox that healthcare, while dedicated to safeguarding health, inadvertently contributes to environmental degradation through waste accumulation and disposal. The analysis of the relevant literature emphasizes the imperative for an environmentally sustainable approach to dental waste measurement, disposal methods, and comprehensive education for stakeholders. Aligned with the World Conference on Sustainable Development and the United Nations’ 2030 Agenda, the study adhered to PRISMA-ScR systematic review guidelines and the Institute of Medicine’s recommendations. The study utilized Medline/PubMed and international organization websites for data retrieval, employing Boolean operator queries in Medline. The systematic literature analysis identified six cross-sectional studies (2004–2023) highlighting variations in dental waste composition due to the lack of standardized identification methods. This heterogeneity underscores the need for a proposed research model, emphasizing comprehensive methodologies and healthcare staff training in waste management, thus transforming the analysis into a scoping review. The study advocates for environmentally conscious dental practices, contributing to broader sustainable healthcare goals through sharing of a research protocol for dental solid waste management.

This study explores the multifaceted effects of acute physical fatigue on information processing, pain threshold, and muscular performance. Enrolling 28 recreational athletes, we used a high-intensity interval training (HIIT) protocol to induce fatigue and conducted pre- and post-intervention assessments. Our findings revealed significant physiological and performance adaptations following the HIIT sessions. Key observations included increased heart rate and rate of perceived exertion and an enhancement in horizontal jump performance and isometric hand strength but no significant change in cognitive processing speed. Remarkably, participants demonstrated a notable increase in pain threshold and blood lactate levels post-exercise. These results challenge traditional views of fatigue, indicating not only a physiological but also a psychological resilience to high-intensity stress. This study provides new insights into the complex interplay between physical fatigue, cognitive function, and pain perception, highlighting the comprehensive effects of HIIT on both physiological and psychological dimensions of human performance.

Nutrition and dietetic care span various life stages, addressing nutritional needs and exploring factors that shape dietary habits. Globally, an alarming disproportion in food resource distribution, coupled with substandard nutritional intake, underscores profound implications for oral health. This is evident in the facilitation of dental caries development and its repercussions on oral soft tissue integrity. While modern markets offer advanced edible products, their effects on oral health, especially in relation to dental caries, remain uncharted. This narrative literature review pursues a four-fold objective: (a) scrutinizing the repercussions of inadequate nutrition on dental caries, (b) exploring psychological determinants influencing dietary habits contributing to caries development, (c) investigating potential implications of newly devised food products on caries formation, and (d) elucidating the role of dentists as facilitators in promoting oral health practices. A comprehensive search spanning PubMed, Web of Science, and Cochrane Library yielded 46 cohort, cross-sectional research articles and systematic reviews adhering to standardized diagnostic criteria for dental caries evaluation. The results highlight contemporary lifestyles as potent contributors to heightened risk of caries due to suboptimal nutritional quality and nutrient insufficiency. Additionally, concerns have arisen with the advent of synthetically engineered food products, warranting exploration of potential implications for future caries development and global oral health status. This review emphasizes the pivotal role of dietitians–nutritionists and dental professionals in advocating sound nutritional practices specifically geared towards preventing dental caries. Ultimately, this review contributes to the understanding of the intricate interplay between nutrition, oral health, and the imperative role of healthcare professionals in fostering preventive measures.

Nowadays, Magnetic Resonance Imaging (MRI) is considered the gold standard for imaging the brain, spinal cord, musculoskeletal system, head and neck, and complex congenital heart malformations; consequentially, the number of MRI scans in patients with implantable electronic devices has simultaneously increased. During the entire length of the MRI exam, patients are exposed to electromagnetic fields with different characteristics (static, low frequency, radiofrequency fields), which are related to different risks. The scarce available literature about MRI-induced heating on cardiac stents suggests that excessive temperature rise occurs only in unfavorable cases. Ideally, RF safety assessment could be performed during the anamnestic process, but this simulation process’s results are too slow to be performed before patient MRI examination. In this context, we developed a dedicated measurement set-up by focusing our target on the measurement of the heating of a cardiac stent during an MRI examination. Results for the temperature rise trend along the entire stent length during a clinical MRI protocol are shown together with the local Specific Absorption Rate (SAR) values and cumulative equivalent minutes at 43 °C (CEM43°C), in order to ensure the safety of patients with MR-conditional devices, also with a view to not inappropriately preclude their access to MRI scans. The obtained results show that the maximum temperature rise (4.12 °C) is within the limit of 5 °C stated in the stent manual for 15 min of continued scanning with the specific conditions. The maximum temperature rise was in correspondence with the stent tips and calculated SAR confirms the fact that two hotspots are present near the tips of the stent. Finally, the calculated CEM43°C remained well below the proposed threshold for muscle tissue.

This article concerns the diagnostic campaign aimed at analyzing the mural painting representing the iconographic theme of the Deesis of the Church of St. Maria Annunziata, Motta San Giovanni, in the province of Reggio Calabria. In 1951, a flood caused the collapse of the building and the consequent breaking of the apse into two parts. The present study focused on the left side of the apse, hosting the figures of Christ and Mary, in order to plan the best conservation intervention strategy. For this purpose, non-invasive investigations and laboratory analytical methods were conducted in order to characterize the constituent materials and to identify the forms of alteration and degradation present on the surface of the painting. In particular, Raman spectroscopy, optical microscopy, scanning electron microscopy coupled to the chemical analysis by an EDS probe, Fourier-transform infrared spectroscopy and ion chromatography were employed. The results highlighted the presence of a single layer of plaster made with a lime-based binder. The chromatic palette of the painting is characterized by ochres and carbon black mixed with lime to obtain the different shades. Finally, the definition of the nature of the deposits and of the overlaid materials was fundamental in order to identify the best products and methods to restore the readability of the work.

Noise levels in a dental office can be produced by different specialty instruments. Exposure to high levels of noise (unwanted sounds) may cause auditory and non-auditory health problems in dentists. The aim of this study was to (a) measure the noise levels within different clinics and laboratories of the Department of Dentistry, School of Health Sciences of the National and Kapodistrian University of Athens, (b) promote information sharing on this serious health issue among stakeholders, and (c) collect data to organize preventive measures for students and personnel (faculty members, collaborators, administrative, and technical staff). Since the study did not apply to acoustics and acoustic measurements, a digital sound level meter and noise-integrating dosimeters with an analogue electronic transducer were used to collect data from certain postgraduate (PG) and undergraduate (UG) clinics and laboratories (LAB) during peak working periods and with a duration of 1 h per clinic/lab. Both personal (dosimeters) and static (area monitoring) noise exposure assessments were evaluated, resulting in various teaching-related activities in dental clinics. At all locations, the maximum exposure limit value of 87 dB(A) was not exceeded. However, chairside personal measurements during ultrasonic work revealed that the lower exposure action value of 80 dB(A) was exceeded. PG clinics were noisier than UG. LAB training settings, even with the new equipment, were close to the upper exposure limit due to the simultaneous use of airotors. In this context, targeted research and investigations into measures are proposed to safeguard the health and safety of students during their duties at the dental school.

Microbial communities are known to play a principal role in petroleum degradation. This study tries to determine the composition of bacteria in selected crude oil-contaminated soil from Tabasco and Tamaulipas states, Mexico. We determined the microbial populations living under these conditions. We evaluated the structure and diversity of bacterial communities in the contaminated soil samples. The most abundant phylum is proteobacteria. Next Generation Sequencing (NGS) analysis of the sampled soils from both states revealed that this phylum has the most relative abundance among the identified bacteria phyla. The heatmap represented the relative percentage of each genus within each sample and clustered the four samples into two groups. Moreover, this allowed us to identify many genera in alkaline soil from Tamaulipas, such as Skermanella sp., Azospirillum sp. and Unclassified species from the Rhodospirillaceae family in higher abundance. Meanwhile, in acidic soil from Tabasco, we identified Thalassospira, Unclassified members of the Sphingomonadaceae family and Unclassified members of the Alphaproteobacteria class with higher abundance. Alpha diversity analysis showed a low diversity (Shannon and Simpson index); Chao observed species in both Regions. These results suggest that the bacteria identified in these genera may possess the ability to degrade petroleum, and further studies in the future should elucidate their role in petroleum degradation.

Dental caries is a multifactorial disease with multiple risk factors. Vitamin D levels (VDLs) and vitamin D receptor polymorphisms (VDRPs) have been investigated for this reason. The aim of this narrative review is to investigate the relation and the factors affecting vitamin D deficiency (VDD), VDRP, Early Childhood Caries (ECC) and Severe Early Childhood Caries (S-ECC) in children (primary and mixed dentition) and dental caries risk in adults (permanent dentition). Additionally, we present a model incorporating factors and interactions that address this relationship. Methods: Three databases (PubMed/MEDLINE, Web of Science, Cochrane Library) were comprehensively searched until 17 January 2023 using the following keywords: “vitamin D”, “vitamin D receptor polymorphism”, “dental caries”, and “dental caries risk”, finding 341 articles. Two reviewers searched, screened, and extracted information from the selected articles. All pooled analyses were based on random-effects models. Eligibility criteria were articles using dmft/DMFT diagnostic criteria with calibrated examiners, probability sampling, and sample sizes. We excluded studies conducted on institutionalized patients. A total of 32 studies were finally used. Results: In most studies, TaqI, FokI, and BsmI polymorphisms affected the prevalence of dental caries. A strong correlation between ECC, S-ECC, and the prevalence of dental caries was reported in association with VDD and maternal intake of VD in primary dentition. Regarding the influence in mixed dentition, the results were found to be inconclusive. A slight positive influence was reported for permanent dentition. Conclusions: Factors affecting caries risk were maternal intake, socioeconomic factors, and level of VD. There is a certain need for more well-conducted studies that will investigate the association between VDR gene polymorphisms and the prevalence of dental caries in mixed and permanent dentition, specifically in adult patients.

This research concerns a stylistic and archaeometric study of an ancient marble female bust recently discovered by the Trapani Lombardo family of Reggio Calabria (Southern Italy) and delivered to the Superintendency of Archaeology, Fine Arts, and Landscape for the metropolitan city of Reggio Calabria and Vibo Valentia (SABAP). Based on the first technical, stylistic, and iconographic observations made by the competent bodies, it is a half-length portrait bust from the Roman era, which precisely had the function of faithfully reproducing the physiognomy of the depicted subject. The research aimed to establish the authenticity of the artwork and the origin of the raw material, providing indications about the textural and compositional features and of the alteration products as well as identifying traces of any previous restoration interventions. For these purposes, after a preliminary assessment of the state of conservation of the bust using visual inspections supported by a handheld digital microscope, different analytical techniques, including polarized optical microscopy (OM), scanning electron microscopy coupled with energy dispersive spectrometry (SEM-EDX), carbon and oxygen stable isotope ratio determinations (δ13C and δ18O), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FT-IR), were used. The results highlighted the originality of the artifact, thus remarking on the importance of the precious archaeological find to be included in the cataloging of tangible assets in the panorama of Italian cultural heritage.

Basketball is a sport where in order to obtain points, it is necessary to put the ball in the basket. Therefore, basketball players need to shoot the ball accurately. This study aimed to evaluate if there are differences between shooting positions and angles concerning athlete visual behavior. Tobii Pro Glasses 3 was used to measure the number and duration of fixations in the target during shooting movement. The sample included 18 basketball players (10 female and 8 males; 22 ± 3.72 years; 12.5 ± 4.52 years of federated basketball practice) who performed a total of 60 shots in all shooting conditions and positions. Two distances (free throw and 3 points line) and three angles (45°, 90°, and 135°) in the 3 points shot were considered in all three shooting conditions (baseline, simulated opposition, and gym audience noise). Between distances, statistically significant differences occurred in the number and total duration of fixations and shooting accuracy. At a greater distance from the basket, the athlete tended to have less accuracy, as well as a lower number and duration of fixations. Between angles, there was no statistically significant differences, neither a tendency towards lower or higher values between them. Moreover, the shooting accuracy was better when the athlete focused for more time on the target, which occurred in the free throw condition.

Carbazole derivatives have gained a lot of attention in medicinal chemistry over the last few decades due to their wide range of biological and pharmacological properties, including antibacterial, antitumor, antioxidant, and anti-inflammatory activities. The therapeutic potential of natural, semi-synthetic or synthetic carbazole-containing molecules has expanded considerably owing to their role in the pathogenesis and development of diabetes. Several studies have demonstrated the ability of carbazole derivatives to reduce oxidative stress, block adrenergic hyperactivation, prevent damage to pancreatic cells and modulate carbohydrate metabolism. In this survey, we summarize the latest advances in the synthetic and natural carbazole-containing compounds involved in diabetes pathways.

Dental and oral health are considered among the main health issues for migrants and refugees, as access to dental health care services is often expensive and difficult. The study investigates dental and oral health determinants among migrants and refugees in 10 European countries (Austria, Bulgaria, Cyprus, France, Germany, Greece, Italy, Malta, Spain, and Sweden), examining how mental health, legal status, discrimination issues and dental services’ use frequency affect dental health. Methods: A cross sectional study using a purpose-made questionnaire was carried out to assess health status and access, with a dedicated section to measure self-perceived dental health, prevalence of caries, last visit to dentist and anticipated access to dental health services. Multivariable logistic regression models were performed to investigate the impact of quality of life, discrimination, immigration status, and other demographic factors on dental health. Results: About half of the sample suffered from poor dental condition and 22% had never visited a dentist. Migrants with higher educational levels had higher odds of having good dental health (OR = 1.08; 95%CI (1.03, 1.12)) and brushing their teeth daily (OR = 1.1; 95%CI (1.04, 1.17)). Higher general and mental health scores were indicative of better dental condition (general health: OR = 1.02; 95%CI (1.01, 1.03); mental health: OR = 1.01; 95%CI (1.004, 1.02)) and higher probability of daily teeth brushing (general health: OR = 1.02; 95%CI (1.01, 1.03); mental health: OR = 1.02; 95%CI (1.01, 1.03)). The possession of any kind of legal immigration permission and not having any children showed similar results. Age and discrimination were correlated with decreased likelihood for good dental conditions. Gender was correlated with daily teeth brushing, as female migrants had higher odds of brushing their teeth daily. Conclusions: Many migrants report poor dental health. Nonetheless, migrants with higher education levels, legal immigration status, better general and mental health, no children, lower sense of discrimination, younger age, and regular dental visits were positively correlated to good dental health (perceived as no dental caries).

The analysis of racket stiffness effect on muscle activity during movement associated with badminton is essential for a better understanding of which badminton racket is better for the athletes to use. The present study aimed to evaluate the effect of racket stiffness on muscle activity and activation time of the upper limb muscles—biceps (Bicp), lateral head (TLat) and long head (TLong) of the triceps—when performing the backhand smash (BH) movement using two rackets with different levels of stiffness. A group of 6 volunteers, with an average age of 21.8 (±4.5) years, and an average badminton practice time of 10.7 (±5.3) years, performed 10 valid repetitions of the movement with each racket, and the muscle activity was collected using surface electromyography. Observing the results shows that the most excited muscle in the BH smash, in terms of (%MVC), is the TLat, regardless of the stiffness of the racket, which shows 56.9% for the Duora 33 and about 68.9% for the Duora 88, comparing with the Bicp and the TLong, respectively. Also, it was observed that the more rigid racket (Duora 88) showed a higher muscular activity for the Bicp and TLat muscles.

Background: The aim of this review was to collect and systematize results of studies from the last 5 years concerning the influence of the Pilates method (PM) on functional body composition (FBC). Methods: The criteria of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) were used in this review. We conducted research in three scientific databases: (i) Web of Science Core Collection, (ii) SCOPUS, and (iii) search directory of the library catalog of the Faculty of Sport and Physical Education of the University of Coimbra—EBSCO Discovery Services. We found 334 articles, covering the period between 1 January 2017 and 31 December 2021. After the selection process, we found 33 eligible articles. Results: The main results seem to point to a tendency to get a better body weight and body fat percentage (BFP), hip circumference (HC), waist, and skinfolds from the chest, abdomen, triceps, and supra-iliac in mostly female samples. Available evidence indicates that, in body composition (BC) and FBC, Pilates practice tends to be effective in reducing obesity as a multifactorial condition. Conclusions: It is concluded that there is a marked trend in the benefits of Pilates in FBC, which is in line with other systematic reviews at the BC level (which includes body weight (BW) and body mass index (BMI)) and in the reduction of the percentage of fat mass (FM). It is also concluded that there is a vast lack of studies on the male population, preventing further scientific development in this area. The limitations of this systematic review can be overcome with studies that bring together multidisciplinary aspects of FBC, better designed and methodologically more robust, which will allow more reliable analyses for the implementation of the Pilates method in terms of FBC. In addition, further studies with a male sample or mixed samples (men vs. women) could confirm the trend of no gender differences in the benefits of Pilates practice.

In daily life, we perform several tasks simultaneously, and it is essential to have adequate postural control to succeed. Furthermore, when performing two or more tasks concurrently, changes in postural oscillation are expected due to the competition for the attentional resources. The aim of this study was to evaluate and compare the center of pressure (CoP) behavior and the hemodynamic response of the prefrontal cortex during static postural standing while performing cognitive tasks of increasing levels of difficulty on a smartphone in young adults. Participants were 35 healthy young adults (mean age ± SD = 22.91 ± 3.84 years). Postural control was assessed by the CoP analysis (total excursion of the CoP (TOTEX CoP), displacements of the CoP in medial–lateral (CoP-ML) and anterior–posterior (CoP-AP) directions, mean total velocity displacement of CoP (MVELO CoP), mean displacement velocity of CoP in medial–lateral (MVELO CoP-ML) and anterior–posterior (MVELO CoP-AP) directions, and 95% confidence ellipse sway area (CEA)), the hemodynamic response by the oxyhemoglobin ([oxy-Hb]), deoxyhemoglobin ([deoxy-Hb]), and total hemoglobin ([total-Hb]) concentrations using a force plate and functional near-infrared spectroscopy (fNIR), respectively. The results showed that the difficult cognitive task while performing static postural standing caused an increase in all CoP variables in analysis (p < 0.05) and of [oxy-Hb] (p < 0.05), [deoxy-Hb] (p < 0.05) and [total-Hb] (p < 0.05) compared to the postural task. In conclusion, the increase in the cognitive demands negatively affected the performance of the postural task when performing them concurrently, compared to the postural task alone. The difficult cognitive task while performing the postural task presented a greater influence on postural sway and activation of the prefrontal cortex than the postural task and the easy cognitive task.

Muscle strength, power, balance and speed assume decisive roles in football performance. This study aims to investigate whether lower limb flexibility, particularly the hip flexors and knee extensor and flexor muscles, are correlated with vertical jump performance, balance and speed in adult football players. A sample of 22 male amateur football players (age: 22.3 ± 3 years; height: 175.4 ± 7.4 cm; weight: 74.9 ± 11.6 kg; BMI: 24.2 ± 2.6 kg/m2) were assessed for lower limb flexibility, vertical jump, balance and speed. Results indicated that vertical jump ability is moderately correlated with left knee extensors flexibility (ρ = −0.426; p = 0.048), which did not occur on the right side. There were no statistically significant correlations between vertical jump and knee flexors flexibility (ρ = 0.330; p = 0.133). In balance, the reaching distance on the right side presented a moderate and statistically significant correlation with the knee flexors flexibility (ρ = 0.411; p = 0.040), which was not observed on the left side. Velocity was not correlated with the knee extensors flexibility (right: ρ = 0.360; p = 0.100; left: ρ = 0.386; p = 0.076), or with the knee flexors flexibility (ρ = −0.173; p = 0.440). In conclusion, the influence of flexibility on vertical jump ability, balance and speed appears to exist. Further research should seek to clarify the associations between these abilities.

Physical fitness and motor skills are considered important attributes for the military, affecting their professional performance. The high physical and psychological demand that the special forces are subjected to requires the acquisition of a set of volitional skills such as resilience, effort, perseverance, or resistance to frustration, which are worthy of further research. This study aimed to analyse the perception of the special troops (commandos) in physical fitness, motor control and psychological skills. A total of 35 male soldiers that ended the commando recruit training program (21.69 ± 2.36 years old) were investigated. A questionnaire was applied to verify differences in perception of physical fitness, motor capacity, physical effort and military training during recruit training according to age, education, work experience and sports background. Descriptive statistics were used to characterize the participants. All data collected were analysed using IBM-SPSS Statistics, version 24. Our results revealed differences in the importance given to the training of motor skills within military training (χ2 = 19.284; p = 0.023), conditional motor skills – speed (χ2 = 17.378; p = 0.043), coordinative motor skills—motor control (χ2 = 20.616; p = 0.014), psychological skills in a military context (χ2 = 13.730; p = 0.008), volitional skills—resistance to frustration (χ2 = 21.568; p = 0.043) and volitional skills—psychological resistance (χ2 = 29.144; p = 0.004). The participants highlighted the importance of instructors having scientific knowledge in physical education to provide military physical training to be better prepared for this purpose. We concluded that motor skills and psychological abilities tend to be equally important in the context of military training. Physical fitness and motor skill development can be considered essential in military training for most of the inquired participants.

Nanophotonics is an emerging multidisciplinary frontier of science and engineering [...]

Oral rehabilitation is a main branch of dentistry focused on diagnosing the patient’s problem and creating a treatment plan to restore aesthetics, recondition morphologically all components, and recover the functionality of the oral cavity. Biological compatibility of the materials used has a major importance, due to the direct contact with essential tissues, such as the soft and hard tissue of the periodontium and the potential influence on the outcome of the treatment. The present material aims to assess the inflammatory response after subcutaneous implantation of three materials frequently used in endodontics (Mineral Trioxide Aggregate—MTA, DiaRoot BioAggregate, and Sealapex). The evaluation of the reparative tissue reaction after 7, 30, and 60 days, respectively, subsequent to in vivo implantation, was carried out through electron microscopy imaging. Moreover, evaluation of the dynamics of the osteogenesis process was an indicator for the maintenance of internal homeostasis in the context of complex intraoral rehabilitation treatments that include fixed prosthodontics correlated with the particular periodontal-aesthetic aspects and completed by cranio-mandibular repositioning. Our study showed increased absolute values of alkaline phosphatase in all material-implanted cases (more pronounced in MTA and Bio Aggregate), highlighting that this enzyme could be an effective indicator of bone formation, which takes place after the material implantation, with the most significant elevated values at 30 days postoperatively.

The aim of this Special Issue is to bring the most updated information on the innovative field of oral and general health coaching and nutritional education strategies for better oral and general health [...]

Golf putting occurs under highly variable conditions. Therefore, adapting to different putting distances is a challenge that the golfer faces and understanding the variables underlying performance in this task is important. The main objective of this study was to analyse the golf-putting performance in skilled golfers at different distances to the hole. Fourteen highly skilled golfers, adult male and right-handed (41.5 ± 13.2 years with an average handicap of 2.3 ± 1.7) performed the golf putting on a natural grass green, completing a total of 120 randomly ordered trials, 30 trials at each of the four different practice conditions (1, 2, 3, and 4 m away from the hole). A smart engineered putter (InPutter) was used as the data acquisition instrument to record several process variables at 100 Hz. Results indicated that golf-putting distances constrained movement organisation variables in specific ways. For example, as the distance to the hole changes, so do the informational constraints, shaping how a golfer needs to regulate performance. We concluded that the effects of different golf-putting distances required the implementation of functional solutions uniquely adjusted to each player. Furthermore, the perception that the player withdrew from the properties of the context (e.g., distance to the hole) was important to adapt the golf-putting process variables (e.g., amplitude and duration of the movement, among others). All these factors led to a decisive influence on how the golfer hit the ball and adjusted his performance. A major implication of developing a better understanding of the role of performance in golf putting is that coaches and players should allow functional movement behaviours to emerge during practice.

To study the antibacterial effect of different Greek honeys, samples of citrus honey, Saturja spp. Honey, and oregano and sage honey were collected directly from producers. Manuka honey and artificial honey were used as controls. The honeys were diluted in various concentrations to determine the minimum inhibitory concentration (MIC) and were also placed in agar wells to determine the inhibitory zones of growth. The bacteria tested were two reference strains and five pathogens isolated from patients with various dental ailments. A series of samples were diluted with artificial saliva instead of distilled water to simulate the conditions in the oral cavity. The results show that in most cases the Greek honeys, and particularly the citrus honey and the oregano and sage honey, outperformed the antibacterial activity of manuka honey against all tested bacteria. This performance was due to the hydrogen peroxide as well as to other components of the honeys, that is, peptides and other substances such as phenolic compounds and flavonoids. Artificial saliva enhanced the antibacterial effect of the honeys in comparison to distilled water.

Background: Foot postural alignment has been associated with altered gait pattern. This study aims to investigate gait kinematic differences in flatfoot subjects’ regarding all lower limb segments compared to neutral foot subjects. Methods: A total of 31 participants were recruited (age: 23.26 yo ± 4.43; height: 1.70 m ± 0.98; weight: 75.14 kg ± 14.94). A total of 15 subjects were integrated into the flatfoot group, and the remaining 16 were placed in the neutral foot group. All of the particpants were screened using the Navicular Drop Test and Resting Calcaneal Stance Position test to characterize each group, and results were submitted to gait analysis using a MOCAP system. Results: Significant kinematic differences between groups were found for the ankle joint dorsiflexion, abduction, and internal and external rotation (p < 0.05). Additionally, significant differences were found for the knee flexion, extension, abduction, and external rotation peak values (p < 0.001). Significant differences were also found for the hip flexion, extension, external rotation, pelvis rotation values (p < 0.02). Several amplitude differences were found concerning ankle abduction/adduction, knee flexion/extension and abduction/adduction, hip flexion/extension and rotation, and pelvis rotation (p < 0.01). Conclusion: Flatfooted subjects showed kinematic changes in their gait patterns. The impact on this condition on locomotion biomechanical aspects is clinically essential, and 3D gait biomechanical analysis use could be advantageous in the early detection of health impairments related to foot posture.

Probiotic therapy forms a new strategy for dental caries prevention. Probiotic microorganisms possess the ability to displace cariogenic microorganisms and colonize the oral cavity. They can produce various antimicrobial substances such as bacteriocins, bacteriocin-like peptides, lactic acid, and hydrogen peroxide. Dairy products may be ideal for probiotic administration in dental patients. Many other means have been proposed, primarily for those allergic to dairy components, such as capsules, liquid form, tablets, drops, lozenges, sweetened cakes, and ice creams. The last two forms can be used in a coaching approach for children and elderly patients who find it difficult to avoid sugary beverages in their daily routine and benefit from the suggestion of easy, cheap, and common forms of delicacies. In caries prevention, the concept of the effector strain is already considered an integral part of the contemporary caries cure or prevention strategy in adults. Adults, though, seem not to be favored as much as children at early ages by using probiotics primarily due to their oral microbiome’s stability. In this non-systematic review we describe the modes of action of probiotics, their use in the cariology field, their clinical potential, and propose options to prevent caries through a patient coaching approach for the daily dental practice.

β-Adrenergic receptors (β-ARs) are G protein-coupled receptors involved in important physiological and pathological processes related to blood pressure and cardiac activity. The inhibition of cardiac β1-ARs could be beneficial in myocardial hypertrophy, ischemia and failure. Several carbazole-based compounds have been described as promising β-blockers. Herein, we investigate the capability of a carbazole derivative and three simplified indole analogs to interact with the active binding site of β1-AR by molecular docking studies. In the light of the obtained results, our compounds were tested by biological assays in H9c2 cardiomyocytes exposed to isoproterenol (ISO) to confirm their potential as β1-blockers agents, and two of them (8 and 10) showed interesting and promising properties. In particular, these compounds were effective against ISO-dependent in vitro cardiac hypertrophy, even at concentrations lower than the known β-AR antagonist propranolol. Overall, the data suggest that the indole derivatives 8 and 10 could act as potent β1-blockers and, active at low doses, could elicit limited side effects.

In the last decade, stimulated Raman scattering (SRS) imaging has been demonstrated to be a powerful method for label-free, non-invasive mapping of individual species distributions in a multicomponent system. This is due to the chemical selectivity of SRS techniques and the linear dependence of SRS signals on the individual species concentrations. However, even if significant efforts have been made to improve spectroscopic coherent Raman imaging technology, what is the best way to resolve overlapped Raman bands in biological samples is still an open question. In this framework, spectral resolution, i.e., the ability to distinguish closely lying resonances, is the crucial point. Therefore, in this paper, the interplay among pump and Stokes bandwidths, the degree of chirp-matching and the spectral resolution of femtosecond stimulated Raman scattering microscopy are experimentally investigated and the separation of protein and lipid bands in the C-H region, which are of great interest in biochemical studies, is, in principle, demonstrated.

Basketball is a team sport in which the players undergo rapid reactions, and running efforts are usually carried out in all directions. The main goal of the present study was to evaluate the muscle activity response in different basketball movements, considering two types of athletes with different levels of experience. Using a group of nine volunteers, female athletes from a senior basketball team, a data acquisition protocol was defined to identify the changes that occurred throughout the sports season. In this study, to assess the gastrocnemius muscle activity, intensity peak (%MC) and time to peak (TP) were evaluated for five typical basketball skills and movements involving running and jumping with and without the ball. Seven repetitions were executed for each movement, performed at two different time-points of the sports season: at the beginning of the teams’ competition, in November (T1), and at the season peak, in March (T2). TP presents greater values for T2 of the season when compared with T1. The results show that the level of experience of the athletes has a significant effect on the results of TP and %MC, particularly when comparing the two seasons.

Background: Recent studies have highlighted the potentialities of a radiobiological parameter, the early regression index (ERITCP), in the treatment response prediction for rectal cancer patients treated with chemoradiotherapy followed by surgery. The aim of this study is to evaluate the performance of this parameter in predicting pathological complete response (pCR) in the context of low field MR guided radiotherapy (MRgRT) for cervical cancer (CC). Methods: A total of 16 patients affected by CC were enrolled. All patients underwent a MRgRT treatment, with prescription of 50.6 Gy in 22 fractions. A daily MR acquisition was performed at simulation and on each treatment fraction. Gross tumor volume (GTV) was delineated on the MR images acquired at the following biological effective dose (BED) levels: 14, 28, 42, 54 and 62 Gy. The ERITCP was calculated at the different BED levels and its predictive performance was quantified in terms of receiver operating characteristic (ROC) curve. Results: pCR was observed in 11/16 cases. The highest discriminative power of ERITCP was reported when a BED value of 28 Gy is reached, obtaining an area under curve (AUC) of 0.84. Conclusion: This study confirmed ERITCP as a promising response biomarker also for CC, although further studies with larger cohort of patients are recommended.

Background: This systematic review summarizes the current knowledge on the superimposition of three-dimensional (3D) diagnostic records to realize an orthodontic virtual patient. The aim of this study is to analyze the accuracy of the state-of-the-art digital workflow. Methods: The research was carried out by an electronic and manual query effectuated from ISS (Istituto Superiore di Sanità in Rome) on three different databases (MEDLINE, Cochrane Library and ISI WEB OF SCIENCE) up to 31st January 2020. The search focused on studies that superimposed at least two different 3D records to build up a 3D virtual patient—information about the devices used to acquire 3D data, the software used to match data and the superimposition method applied have been summarized. Results: 1374 titles were retrieved from the electronic search. After title-abstract screening, 65 studies were selected. After full-text analysis, 21 studies were included in the review. Different 3D datasets were used: facial skeleton (FS), extraoral soft tissues (ST) and dentition (DENT). The information provided by the 3D data was superimposed in four different combinations: FS + DENT (13 papers), FS + ST (5 papers), ST + DENT (2 papers) and all the types (FS + ST + DENT) (1 paper). Conclusions: The surface-based method was most frequently used for 3D objects superimposition (11 papers), followed by the point-based method (6 papers), with or without fiducial markers, and the voxel-based method (1 paper). Most of the papers analyzed the accuracy of the superimposition procedure (15 papers), while the remaining were proof-of-principles (10 papers) or compared different methods (3 papers). Further studies should focus on the definition of a gold standard. The patient is going to have a huge advantage from complete digital planning when more information about the spatial relationship of anatomical structures are needed: ectopic, impacted and supernumerary teeth, root resorption and angulations, cleft lip and palate (CL/P), alveolar boundary conditions, periodontally compromised patients, temporary anchorage devices (TADs), maxillary transverse deficiency, airway analyses, obstructive sleep apnea (OSAS), TMJ disorders and orthognathic and cranio-facial surgery.

The application of titanium oxide nanotubes for the removal of contaminants from freshwater is a rapidly growing scientific interest, especially when it comes to water conservation strategies. In this study we employed four different titanium oxide nanotube surfaces, prepared by a two-electrode anodic oxidation. Two of the surfaces were synthesised in aqueous media, while the other two surfaces were synthesised in ethylene glycol. One of the arrays synthesised in the organic medium was impregnated with silver nanoparticles, while the remaining surfaces were not. The chemical reactivity of the various surfaces was assessed using 2,2-Diphenyl-1-picrylhydrazyl (DPPH) and 2,2’-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) as free electron sensitive probe molecules, in parallel with tannic acid degradation and copper ion reducing capacity. The potential antimicrobial activity of the surfaces was assessed against a panel of microorganisms composed of yeast, fungi, Gram-positive and Gram-negative bacteria. Field emission scanning electron microscopy revealed that surfaces produced in the aqueous medium had a smaller tube length and a smaller tube diameter. It was noted that one of the materials using sodium sulfate as the supporting electrolyte had the most irregular nanostructure morphology with tubes growing to the side rather than vertically. The structural variation of the surfaces directly reflected both the chemical and biological activity, with the nanotubes formed in ethylene glycol showing the fastest rates in the stabilization of DPPH and ABTS radicals, the fastest tannic acid decomposition under various pH conditions and the fastest metal reducing activity. Furthermore, the surface containing silver and its bare counterpart showed the most effective antimicrobial activity, removing approximately 82% of Gram-negative bacteria, 50% of Gram-positive bacteria, 70% of yeast and 40% of fungi, with Gram-negative bacteria being the most susceptible to these surfaces.

Health-related behavior based on diet is an important determinant of oral health in independent elderly. Aging impairs senses, mastication, oral status, and function, causing nutritional needs and diet insufficiencies that contribute to a vicious circle of impairment. But the present needs of independent older adults suggest that health research and oral health care should shift from disease management and therapy to integral customized and personal treatment plans, including lifestyle, psychological, nutritional, and oral health coaching approaches. In this paper health coaching approaches in medical and dental settings are valued as to their effectiveness for older adults. Furthermore, coaching approaches for seniors are discussed and coaching models for better senior patient-dentist cooperation on the diet issue are suggested. Diet and oral health coaching is proven to be a modern senior patient-centered approach that needs to be incorporated at all relevant settings. It should aim to empower older adults in co-management of their oral diseases or bad diet habits affecting their oral health. This can be carried out through an incorporated educational plan for dentists either at the postgraduate or professional level since advantages seem to enhance the quality of life of the independent elderly.

In the present paper, an innovative, recently patented technique for the construction of a curved structural member without scaffolds is proposed and illustrated. It consists of a Hinged Lifting Arch (HLA), using Fiber-Reinforced Polymer (FRP) bonded strips. In detail, a series of blocks are cut following an arch geometry and then aligned on the ground floor to bond a composite on their top surface. Moreover, impregnation of the polymeric adhesive is not allowed at the extremities of each block. The fiber sheet is applied continuously along the entire extrados. In this context, hinges are introduced, and the FRP-connected blocks can easily rotate in the opposite direction around the contact ends (i.e., hinges). Finally, the middle block is lifted up, and the arch takes the desired shape. Moreover, an analytical model is proposed and discussed for designing the proper aspect ratio of the blocks in order to ensure full mutual contact when the HLA is completely lifted. The advantages of the proposed technique relate to the absence of scaffolds and improved seismic strength against horizontal loads, thanks to the presence of the FRP, which limits the occurrence of hinges at the extrados.

Polarization-sensitive digital holographic imaging (PS-DHI) is a recent imaging technique based on interference among several polarized optical beams. PS-DHI allows simultaneous quantitative three-dimensional reconstruction and quantitative evaluation of polarization properties of a given sample with micrometer scale resolution. Since this technique is very fast and does not require labels/markers, it finds application in several fields, from biology to microelectronics and micro-photonics. In this paper, a comprehensive review of the state-of-the-art of PS-DHI techniques, the theoretical principles, and important applications are reported.

We investigated the blood flow patterns and the hemodynamics associated with an abdominal aortic aneurysm detected in an in vitro measurement campaign performed in a laboratory model of an aneurysm with rigid walls and an axisymmetric shape. Experiments were run in steady flow conditions and by varying the Reynolds number in the range 410 < Re < 2650. High spatial and temporal resolution 2D optical measurements of the velocity field were obtained through a particle tracking technique known as Hybrid Lagrangian Particle Tracking. Conversely to classical Particle Image Velocimetry, both the fluid particle trajectories and the instantaneous and time-averaged velocity fields are provided without constraints on the grid size and very close to the vessel boundary. All the most relevant quantities needed to investigate the flow features were evaluated, and in particular, we focused on the wall shear stress distribution both in the healthy aortic portion and within the aneurysm. Results show that the recirculation zone in correspondence of the cavity moves downstream, and this displacement is found to increase with Re. Very low wall shear stress values are recovered in correspondence of the aneurysmal cavity, while a sharp peak occurs in correspondence of the reattachment point. In agreement with the literature data, the peak value is found to decrease with Re and to be about equal to twice the upstream value.

We investigate the enhancement of second-harmonic generation in cylindrical GaAs nanowires. Although these nanostructures confine light in two dimensions, power conversion efficiencies on the order of 10 − 5 with a pump peak intensity of ~ 1 GW / cm 2 are possible if the pump and the second-harmonic fields are coupled to the Mie-type resonances of the nanowire. We identify a large range of nanowire radii in which a double-resonance condition, i.e., both the pump and the second-harmonic fields excite normal modes of the nanowire, induces a high-quality-factor peak of conversion efficiency. We show that second-harmonic light can be scattered with large efficiency even if the second-harmonic photon energy is larger than 1.42 eV, i.e., the electronic bandgap of GaAs, above which the material is considered opaque. Finally, we evaluate the efficiency of one-photon absorption of second-harmonic light and find that resonant GaAs nanowires absorb second-harmonic light in the near-field region almost at the same rate at which they radiate second-harmonic light in the far-field region.

The enhanced post-cracking properties of fiber-reinforced concrete (FRC), as compared to plain concrete (PC), are extensively proven by many experimental findings. However, still limited experimental data are available on the behavior of such materials in long-term conditions and durability. This paper shows results from a study lasting for about seven years, which was for a final discussion on the behavior in the short and long-term of steel and polyester FRC beams with conventional steel reinforcement, after being exposed to sustained service loading and natural environmental agents for 72 months. After 28 days of curing in laboratory conditions, the beams were moved to the exposure site and loaded up to service conditions. The evolution of the crack pattern was monitored and recorded over time. After this long exposure the beams were subjected to a four point bending test in order to evaluate their residual mechanical behavior. Eventually, the beams were cut, in order to carry out durability tests for the evaluation of the carbonation depth and chloride penetration. The experimental results highlight the favorable effects of short fibers in reducing crack width and enhancing flexural stiffness. The presence of short structural fibers appears also to play a useful role in delaying creep effects inside the concrete beams. Finally, the experimental cracking behavior is compared with the one computed by applying the fib Model Code 2010 for the bearing capacity and crack width prediction.

In this study, we present a two-dimensional dielectric grating which allows achieving high absorption in a monolayer graphene at visible and near-infrared frequencies. Dielectric gratings create guided-mode resonances that are exploited to effectively couple light with the graphene layer. The proposed structure was numerically analyzed through a rigorous coupled-wave analysis method. Effects of geometrical parameters and response to the oblique incidence of the plane wave were studied. Numerical results reveal that light absorption in the proposed structure is almost insensitive to the angle of the impinging source over a considerable wide angular range of 20°. This may lead to the development of easy to fabricate and experimentally viable graphene-based absorbers in the future.

Generally, to reduce the area of a photovoltaic cell, which is typically very expensive, solar concentrators based on a set of mirrors or mechanical structures are used. However, such solar concentrators have some drawbacks, as they need a tracking system to track the sun’s position and also they suffer for the overheat due to the concentration of both light and heat on the solar cell. The fundamental advantages of volume holographic optical elements are very appealing for lightweight and cheap solar concentrators applications and can become a valuable asset that can be integrated into solar panels. In this paper, a review of volume holographic-based solar concentrators recorded on different holographic materials is presented. The physical principles and main advantages and disadvantages, such as their cool light concentration, selective wavelength concentrations and the possibility to implement passive solar tracking, are discussed. Different configurations and strategies are illustrated and the state-of-the-art is presented including commercially available systems.

Enhancing the second harmonic conversion efficiency at the nanoscale is a critical challenge in nonlinear optics. Here we propose the use of epsilon-near-zero materials to boost the nonlinear radiation in the far field. Here, a comparison of the second harmonic behavior of a cylindrical AlGaAs nanoantenna placed over different semi-infinite layers is presented. In particular, we observed that the second harmonic generation is strongly enhanced and redirected by the simultaneous presence of a resonance at the fundamental wavelength and a low-permittivity condition in the substrate at the harmonic wavelength. Our results pave the way for a novel approach to enhance optical nonlinearities at the nanoscale.

In recent years, even if Fiber Reinforced Polymer (FRP) composites have been widely used for strengthening of civil buildings, a new generation of materials has been studied and proposed for historical masonry construction. These buildings, mainly made of stone work, are common in many areas of Europe and Asia and recent earthquakes has been the cause of many catastrophic failures. The brittleness of unreinforced historic masonry can be considerably reduced using new retrofitting lighter-weight materials such FRP, even if limitations were evidenced due to material and mechanical compatibility with poor substrates. Thus, fibrous reinforcements were used as long fibres incorporated into a cement or lime matrix, which better match with the properties of ancient masonry. The use of low strength fibers such as glass and basalt, respect to carbon, in presence of an alkaline matrix brought out durability issues, due to the chemical vulnerability of common glass and basalt fibres. The objective of this research is to explore the effects of selected aqueous environments and fatigue loading on the mechanical and physical properties of composite grids, made of E-CR (Electrical/Chemical Resistance) glass fibers and epoxy-vinylester resin, used as tensile reinforcement in new composite reinforced mortar systems. Glass-fiber-reinforced polymer (GFRP) coupons were subjected to tensile testing and a severe protocol of durability tests, including alkaline environment and fatigue tensile loads. Accelerated ageing tests were used to simulate long-term degradation in terms of chemical attack and consequent reduction of tensile strength. The ageing protocol consisted of immersion at 40 °C in alkaline bath made by deionized water and Ca(OH)2, 0.16% in weight, solution for 30 days. GFRP specimens aged and unaged were also tested under tensile fatigue cycles up to 1,000,000 cycles and a nominal frequency of 7.5 Hz. After this severe conditioning the tests indicate a good tensile strength retention of the GFRP in absence of fatigue loads, while a significant loss in fatigue life was experienced when both alkaline exposure and fatigue loads were applied.