1. Monitoring recovery after laser surgery of the breast with optical tomography: a case study.
- Author
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Hebden JC, Yates TD, Gibson A, Everdell N, Arridge SR, Chicken DW, Douek M, and Keshtgar MR
- Subjects
- Adult, Algorithms, Breast Neoplasms diagnostic imaging, Female, Fibroadenoma diagnostic imaging, Follow-Up Studies, Humans, Prognosis, Reproducibility of Results, Sensitivity and Specificity, Treatment Outcome, Ultrasonography, Breast Neoplasms pathology, Breast Neoplasms surgery, Fibroadenoma pathology, Fibroadenoma surgery, Image Interpretation, Computer-Assisted methods, Laser Therapy methods, Tomography, Optical methods
- Abstract
Results are presented of a study to monitor the changes in the optical properties of breast tissue over a 12-month period after interstitial laser photocoagulation treatment of a fibroadenoma. The study involved generating cross-sectional images of the breast with a multichannel time-resolved imaging system and a nonlinear image reconstruction algorithm. Images of the internal absorbing and scattering properties revealed the expected initial inflammatory response, followed by the development of low-scattering cysts consistent with corresponding ultrasound examinations. Although results indicate that purely qualitative images can potentially provide clinically valuable data, means of enhancing diagnostic information by overcoming present limitations of the approach are discussed.
- Published
- 2005
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