Search

The Talbot effect and moire fringes are combined to measure the refractive indices of a birefringent material. Techniques based on the visibility of moire fringes in finite fringe mode and based on fringe count are presented. These techniques are sensitive and advantageous. They are described and analyzed. [C] 2001 Optical Society of America OCIS codes: 120.3180, 120.3940, 120.4120, 120.4290, 120.4630, 120.4640.

Intraoperative delineation of breast cancer is a major challenge. An effective breast tissue screening technique may reduce the risk of re-excision during surgery by specifically identifying positive margins. In this study, a high-resolution automated full-field polarization-sensitive optical coherence tomography (FF-PS-OCT) system was developed to classify healthy and malignant human breast tissue from quantitative phase retardation information of the tissues in ex vivo. Twelve breast tissue samples [four healthy, eight malignant (cancerous)] were imaged with the FF-PS-OCT system and the different phase features were extracted from the acquired OCT images (106), based on the differences in the optical signatures of the healthy and malignant tissues. A linear support vector model classifier was trained using 75 images, with a sensitivity of 92.10% and specificity of 89.18% was achieved. Thirty-one images were used to test the model, with a sensitivity of 90.90% and specificity of 85.0% achieved.