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Your search keyword '"Zähner, H."' showing total 4 results
Start Over Author "Zähner, H." Journal applied microbiology and biotechnology
4 results on '"Zähner, H."'

3. Production of desferrioxamine E and new analogues by directed fermentation and feeding fermentation.

Author

Meiwes J, Fiedler HP, Zähner H, Konetschny-Rapp S, and Jung G

Subjects
Bacteriological Techniques, Chromatography, High Pressure Liquid, Culture Media, Deferoxamine isolation & purification, Hydrogen-Ion Concentration, Iron metabolism, Lysine metabolism, Streptomyces growth & development, Sucrose metabolism, Deferoxamine metabolism, Fermentation, Streptomyces metabolism
Abstract

Streptomyces olivaceus TU 2718 produces the siderophore desferrioxamine E. Production depends on L-lysine and iron concentrations in the medium. With optimized conditions the yield of desferrioxamine E could be increased to 12 g/l in feeding fermentations. Supplementation of the basic production medium with natural and synthetic precursors of desferrioxamine E led to the production of twelve new analogues of desferrioxamine E.

Published
1990
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4. Comparative studies on the fermentative production of lantibiotics by staphylococci.

Author

Hörner T, Ungermann V, Zähner H, Fiedler HP, Utz R, Kellner R, and Jung G

Subjects
Alanine analogs & derivatives, Alanine metabolism, Amino Acid Sequence, Bacteriocins, Chromatography, Gel, Culture Media, Microbial Sensitivity Tests, Molecular Sequence Data, Peptide Biosynthesis, Peptides, Cyclic biosynthesis, Peptides, Cyclic metabolism, Sulfides, Anti-Bacterial Agents, Fermentation physiology, Peptides, Staphylococcus metabolism, Staphylococcus epidermidis metabolism
Abstract

The production of the lanthionine-containing polypeptide antibiotics gallidermin from Staphylococcus gallinarum TU 3928 and pep 5 from S. epidermidis 5 is investigated with respect to regulation and stimulation of productivity by media components, optimization of both the media used and the fermentation process and is compared to the production of the lantibiotic epidermin from S. epidermidis TU 3298. Efficient methods for rapid quantification of lantibiotics, optimization of the media and a primary enrichment by adsorption chromatography are reported.

Published
1990
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