1. Biotechnological production of 2-phenylethanol
- Author
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W. Bluemke, Dieter Sell, Jens Schrader, and M. M. W. Etschmann
- Subjects
Phenylpyruvate decarboxylase ,Bacteria ,Chemistry ,Bioconversion ,business.industry ,Flavour ,Fungi ,General Medicine ,Phenylethyl Alcohol ,Pulp and paper industry ,Applied Microbiology and Biotechnology ,Biotechnology ,Flavoring Agents ,Biotransformation ,Product inhibition ,Chemical Industry ,Fermentation ,Production (economics) ,business ,Flavor - Abstract
2-Phenylethanol (2-PE) is an important flavour and fragrance compound with a rose-like odour. Most of the world's annual production of several thousand tons is synthesised by chemical means but, due to increasing demand for natural flavours, alternative production methods are being sought. Harnessing the Ehrlich pathway of yeasts by bioconversion of L-phenylalanine to 2-PE could be an option, but in situ product removal is necessary due to product inhibition. This review describes the microbial production of 2-PE, and also summarizes the chemical syntheses and the market situation.
- Published
- 2002