21. Fabrication of Paper-Based Device Using Printing Circuit Technology
- Author
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An Liang Zhang and Yan Zha
- Subjects
Materials science ,Fabrication ,Filter paper ,business.industry ,Microfluidics ,chemistry.chemical_element ,Nanotechnology ,General Medicine ,Thermal transfer ,Paper based ,Blank ,Copper ,chemistry ,Optoelectronics ,Full thickness ,business - Abstract
This paper describes the use of a printing circuit technology to generate hydrophilic channels in a filter paper. Pattern was first designed using Protel soft, and printed on a blank paper. Then, the pattern was transferred on a sheet copper using a thermal transfer printer. The sheet copper with pattern was dipped in a ferric trichloride solution to etch the whole pattern of the sheet copper. At last, the etched sheet copper was coated with paraffin, then with a filter paper and heated at the other side of the sheet copper with an electric iron. The melting paraffin penetrated full thickness of the filter paper and formed a hydrophobic “wall”. Colorimetric assays for the presence of protein and glucose were demonstrated in the paper-based device. The work is helpful for researching paper-based microfluidic devices for monitoring health and detecting disease.
- Published
- 2012