• This manuscript firstly establishes a half vehicle-pavement-continuous beam bridge (VPCB) coupled system analytical model. • It is innovatively that the bridge and vehicle initial conditions are considered into analytical model. • The pavement road surface local deterioration is simulated by increasing the local roughness level of the road surface. At present, the highway bridge field is in a period of vigorous development, and the application of continuous beam bridges is becoming more extensive, so the related safety research is particularly important. However, there are few studies on the vehicle-bridge coupled interaction of continuous beam bridges, and the influence of pavement is not considered. In order to ensure that the theoretical research can better serve the engineering practice, it is urgent to establish a more refined and more complex vehicle-bridge coupled model. In this paper, a vehicle-pavement-continuous beam bridge (VPCB) coupled system model is established. A half-vehicle model is adopted, the pavement is simulated by a continuous and uniform spring damper, and the bridge is a three-span continuous beam bridge. The motion equation of VPCB system is established and deduced using D 'Alembert principle and modal superposition method. The dynamic responses of VPCB system are calculated by Newmark- β method. Here, the continuous beam bridge mode functions are fitted based on the modal vector of the continuous beam calculated by the finite element model. The correctness of the method is verified by existing literatures. The effects of bridge pavement, vehicle speed, bridge second span length, the pavement equivalent spring stiffness coefficient k p and damping coefficient c p , road roughness on VPCB system are studied. The results show that the pavement can reduce the bridge dynamic amplification factor (DAF) and the vehicle acceleration to improve the ride comfort. The dynamic responses of the vehicle and the bridge contain each other's natural frequencies. The responses of VPCB system increase with the vehicle velocity, the vehicle responses are more affected than the bridge responses. The pavement equivalent stiffness and damping coefficient has little effect on the system. The responses of vehicle and bridge increase with the increase of the bridge second span length. When the vehicle travels each span of the three-span continuous beam bridge, the time history curve of the pavement deformation under the tire resembles a sine wave. When the local roughness level of the road surface increases, the system responses at the deteriorated position suddenly increases, and the responses of the subsequent position will also be affected. The larger the roughness grade, the more obvious the responses increase. The effect on the system responses of the whole pavement damage is more significant than the local pavement damage. [ABSTRACT FROM AUTHOR]