1. Sarcopenia is an independent predictor of delayed gastric emptying following pancreaticoduodenectomy: a retrospective study
- Author
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Mohei Kohyama, Ryuta Shintakuya, Tatsuya Tazaki, Masaru Sasaki, Yuki Kaiki, Toshinori Hirano, Yoichi Sugiyama, and Atsushi Nakamitsu
- Subjects
Male ,Sarcopenia ,medicine.medical_specialty ,Gastroparesis ,medicine.medical_treatment ,030230 surgery ,Gastroenterology ,Body Mass Index ,Pancreaticoduodenectomy ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Risk Factors ,Internal medicine ,medicine ,Humans ,Retrospective Studies ,Univariate analysis ,Gastric emptying ,business.industry ,fungi ,General Medicine ,medicine.disease ,Pancreatic Neoplasms ,Gastric Emptying ,Quartile ,Pancreatic fistula ,030220 oncology & carcinogenesis ,Female ,Surgery ,Complication ,business ,Body mass index - Abstract
BACKGROUND The pathogenesis of delayed gastric emptying (DGE), a common complication of pancreaticoduodenectomy, is unclear. Loss of skeletal muscle mass (sarcopenia) is associated with post-pancreaticoduodenectomy complications; however, few studies have investigated the relationship between sarcopenia and DGE. The aim of this study was to investigate whether post-pancreaticoduodenectomy DGE is affected by pre-operative skeletal muscle mass. METHODS We retrospectively analysed the data of 112 consecutive patients who had undergone pancreaticoduodenectomy and divided them into the following two groups: no DGE (n = 100) and with DGE (n = 12). Patients were stratified by quartiles according to each element of body composition. The lowest quartile for skeletal muscle mass was defined as having sarcopenia. RESULTS Ten and two patients had grades B and C DGE, respectively. According to univariate analysis, body mass index (P = 0.031), clinically relevant post-operative pancreatic fistula (P
- Published
- 2019