1. Change in serum albumin level predicts short‐term complications in patients with normal preoperative serum albumin after gastrectomy of gastric cancer
- Author
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Zhouting Zhu, Shangce Du, Shichao Ai, Wenxian Guan, Jiafeng Wang, Feng Sun, Zhengyang Yang, and Zhijian Liu
- Subjects
Male ,medicine.medical_specialty ,medicine.medical_treatment ,Serum albumin ,Gastroenterology ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Gastrectomy ,Predictive Value of Tests ,Risk Factors ,Stomach Neoplasms ,Internal medicine ,medicine ,Humans ,Serum Albumin ,Aged ,Retrospective Studies ,biology ,Receiver operating characteristic ,business.industry ,Area under the curve ,Albumin ,Postoperative complication ,General Medicine ,Odds ratio ,Length of Stay ,Middle Aged ,Confidence interval ,C-Reactive Protein ,Case-Control Studies ,030220 oncology & carcinogenesis ,Preoperative Period ,biology.protein ,Female ,030211 gastroenterology & hepatology ,Surgery ,business - Abstract
BACKGROUND The purpose of this study was to evaluate the correlation between serum albumin level change (ΔALB) and post-operative complications in patients with normal preoperative serum albumin after gastrectomy of gastric cancer. METHODS A total of 193 patients undergoing curative (R0) gastrectomy from September 2015 to May 2017 were enrolled in this study. The risk factors for predicting post-operative complications were identified by univariate and multivariate analysis. The cut-off value and diagnostic accuracy of ΔALB were measured by receiver operating characteristic curves. ΔALB was defined as: (albumin level before surgery - albumin on post-operative day (POD) 1)/albumin level before surgery × 100%. RESULTS A total of 60 patients (31.0%) had post-operative complications. Our results showed that the cut-off value of ΔALB was 19.0%. Using a cut-off value of 19.0%, multivariate analysis identified that ΔALB was able to predict post-operative complications as an independent factor (odds ratio 13.98, 95% confidence interval 6.048-32.32, P
- Published
- 2019
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