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9 results on '"Lee, Sue J"'

1. Pharmacokinetic Study of Rectal Artesunate in Children with Severe Malaria in Africa

Author

Fanello, Caterina, primary, Hoglund, Richard M., additional, Lee, Sue J., additional, Kayembe, Daddy, additional, Ndjowo, Pauline, additional, Kabedi, Charlie, additional, Badjanga, Benjamin B., additional, Niamyim, Phettree, additional, Tarning, Joel, additional, Woodrow, Charles, additional, Gomes, Melba, additional, Day, Nick P., additional, White, Nicholas J., additional, and Onyamboko, Marie A., additional

Published
2021
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2. A Randomized Controlled Trial of Three- versus Five-Day Artemether-Lumefantrine Regimens for Treatment of Uncomplicated Plasmodium falciparum Malaria in Pregnancy in Africa

Author

Onyamboko, Marie A., primary, Hoglund, Richard M., additional, Lee, Sue J., additional, Kabedi, Charlie, additional, Kayembe, Daddy, additional, Badjanga, Benjamin B., additional, Turner, Gareth D. H., additional, Jackson, Nikky V., additional, Tarning, Joel, additional, McGready, Rose, additional, Nosten, Francois, additional, White, Nicholas J., additional, Day, Nicholas P. J., additional, and Fanello, Caterina, additional

Published
2020
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3. Pharmacokinetic Interactions between Primaquine and Pyronaridine-Artesunate in Healthy Adult Thai Subjects

Author

Jittamala, Podjanee, primary, Pukrittayakamee, Sasithon, additional, Ashley, Elizabeth A., additional, Nosten, François, additional, Hanboonkunupakarn, Borimas, additional, Lee, Sue J., additional, Thana, Praiya, additional, Chairat, Kalayanee, additional, Blessborn, Daniel, additional, Panapipat, Salwaluk, additional, White, Nicholas J., additional, Day, Nicholas P. J., additional, and Tarning, Joel, additional

Published
2015
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4. Open-Label Crossover Study of Primaquine and Dihydroartemisinin-Piperaquine Pharmacokinetics in Healthy Adult Thai Subjects

Author

Hanboonkunupakarn, Borimas, primary, Ashley, Elizabeth A., additional, Jittamala, Podjanee, additional, Tarning, Joel, additional, Pukrittayakamee, Sasithon, additional, Hanpithakpong, Warunee, additional, Chotsiri, Palang, additional, Wattanakul, Thanaporn, additional, Panapipat, Salwaluk, additional, Lee, Sue J., additional, Day, Nicholas P. J., additional, and White, Nicholas J., additional

Published
2014
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5. Pharmacokinetic Interactions between Primaquine and Chloroquine

Author

Pukrittayakamee, Sasithon, primary, Tarning, Joel, additional, Jittamala, Podjanee, additional, Charunwatthana, Prakaykaew, additional, Lawpoolsri, Saranath, additional, Lee, Sue J., additional, Hanpithakpong, Warunee, additional, Hanboonkunupakarn, Borimas, additional, Day, Nicholas P. J., additional, Ashley, Elizabeth A., additional, and White, Nicholas J., additional

Published
2014
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6. Randomized, Double-Blind, Placebo-Controlled Trial of Monthly versus Bimonthly Dihydroartemisinin-Piperaquine Chemoprevention in Adults at High Risk of Malaria

Author

Lwin, Khin Maung, primary, Phyo, Aung Pyae, additional, Tarning, Joel, additional, Hanpithakpong, Warunee, additional, Ashley, Elizabeth A., additional, Lee, Sue J., additional, Cheah, Phaikyeong, additional, Singhasivanon, Pratap, additional, White, Nicholas J., additional, Lindegårdh, Niklas, additional, and Nosten, François, additional

Published
2012
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7. Exploring the Contribution of Candidate Genes to Artemisinin Resistance in Plasmodium falciparum

Author

Imwong, Mallika, primary, Dondorp, Arjen M., additional, Nosten, Francois, additional, Yi, Poravuth, additional, Mungthin, Mathirut, additional, Hanchana, Sarun, additional, Das, Debashish, additional, Phyo, Aung Phae, additional, Lwin, Khin Maung, additional, Pukrittayakamee, Sasithon, additional, Lee, Sue J., additional, Saisung, Suwannee, additional, Koecharoen, Kitti, additional, Nguon, Chea, additional, Day, Nicholas P. J., additional, Socheat, Duong, additional, and White, Nicholas J., additional

Published
2010
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8. Pharmacokinetic Interactions between Primaquine and Pyronaridine-Artesunate in Healthy Adult Thai Subjects

Author

Jittamala, Podjanee, Pukrittayakamee, Sasithon, Ashley, Elizabeth A., Nosten, François, Hanboonkunupakarn, Borimas, Lee, Sue J., Thana, Praiya, Chairat, Kalayanee, Blessborn, Daniel, Panapipat, Salwaluk, White, Nicholas J., Day, Nicholas P. J., and Tarning, Joel

Abstract

ABSTRACTPyronaridine-artesunate is a newly introduced artemisinin-based combination treatment which may be deployed together with primaquine. A single-dose, randomized, three-sequence crossover study was conducted in healthy Thai volunteers to characterize potential pharmacokinetic interactions between these drugs. Seventeen healthy adults received a single oral dose of primaquine alone (30 mg base) and were then randomized to receive pyronaridine-artesunate alone (540−180 mg) or pyronaridine-artesunate plus primaquine in combination, with intervening washout periods between all treatments. The pharmacokinetic properties of primaquine, its metabolite carboxyprimaquine, artesunate, its metabolite dihydroartemisinin, and pyronaridine were assessed in 15 subjects using a noncompartmental approach followed by a bioequivalence evaluation. All drugs were well tolerated. The single oral dose of primaquine did not result in any clinically relevant pharmacokinetic alterations to pyronaridine, artesunate, or dihydroartemisinin exposures. There were significantly higher primaquine maximum plasma drug concentrations (geometric mean ratio, 30%; 90% confidence interval [CI], 17% to 46%) and total exposures (15%; 6.4% to 24%) during coadministration with pyronaridine-artesunate than when primaquine was given alone. Pyronaridine, like chloroquine and piperaquine, increases plasma primaquine concentrations. (This study has been registered at ClinicalTrials.gov under registration no. NCT01552330.)

Published
2014
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9. A Randomized Controlled Trial of Three- versus Five-Day Artemether-Lumefantrine Regimens for Treatment of Uncomplicated Plasmodium falciparumMalaria in Pregnancy in Africa

Author

Onyamboko, Marie A., Hoglund, Richard M., Lee, Sue J., Kabedi, Charlie, Kayembe, Daddy, Badjanga, Benjamin B., Turner, Gareth D. H., Jackson, Nikky V., Tarning, Joel, McGready, Rose, Nosten, Francois, White, Nicholas J., Day, Nicholas P. J., and Fanello, Caterina

Abstract

Artemether-lumefantrine antimalarial efficacy in pregnancy could be compromised by reduced drug exposure. Population-based simulations suggested that therapeutic efficacy would be improved if the treatment duration was increased.

Published
2020
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