1. In vitro antibiotic susceptibility of Neisseria gonorrhoeae in Jakarta, Indonesia.
- Author
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Lesmana M, Lebron CI, Taslim D, Tjaniadi P, Subekti D, Wasfy MO, Campbell JR, and Oyofo BA
- Subjects
- Drug Resistance, Microbial, Female, Gonorrhea epidemiology, Humans, Indonesia epidemiology, Microbial Sensitivity Tests, Neisseria gonorrhoeae enzymology, Sex Work, beta-Lactamases metabolism, Anti-Bacterial Agents pharmacology, Gonorrhea genetics, Neisseria gonorrhoeae drug effects
- Abstract
Antibiotic susceptibilities were determined for 122 Neisseria gonorrheae isolates obtained from 400 sex workers in Jakarta, Indonesia, and susceptibilities to ciprofloxacin, cefuroxime, cefoxitin, cefotaxime, ceftriaxone, chloramphenicol, and spectinomycin were found. All isolates were resistant to tetracycline. A number of the isolates demonstrated decreased susceptibilities to erythromycin (MIC >/= 1.0 microg/ml), thiamphenicol (MIC >/= 1.0 microg/ml), kanamycin (MIC >/= 16.0 microg/ml), penicillin (MIC >/= 2.0 microg/ml), gentamicin (MIC >/= 16.0 microg/ml), and norfloxacin (MIC = 0.5 microg/ml). These data showed that certain antibiotics previously used in the treatment of gonorrhea are no longer effective.
- Published
- 2001
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