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Your search keyword '"Crispim, Marcell"' showing total 3 results
Start Over "Crispim, Marcell" Journal antimicrobial agents and chemotherapy
3 results on '"Crispim, Marcell"'

2. An Aromatic Diamidine That Targets Kinetoplast DNA, Impairs the Cell Cycle in Trypanosoma cruzi, and Diminishes Trypomastigote Release from Infected Mammalian Host Cells

Author

Girard, Richard M. B. M., primary, Crispim, Marcell, additional, Stolić, Ivana, additional, Damasceno, Flávia Silva, additional, Santos da Silva, Marcelo, additional, Pral, Eizabeth Mieko Furusho, additional, Elias, Maria Carolina, additional, Bajić, Miroslav, additional, and Silber, Ariel Mariano, additional

Published
2016
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3. A Fluorinated Phenylbenzothiazole Arrests the Trypanosoma cruziCell Cycle and Diminishes the Infection of Mammalian Host Cells

Author

Cuevas-Hernández, Roberto I., Girard, Richard M. B. M., Martínez-Cerón, Sarai, Santos da Silva, Marcelo, Elias, Maria Carolina, Crispim, Marcell, Trujillo-Ferrara, José G., and Silber, Ariel Mariano

Abstract

Chagas disease (CD) is a human infection caused by Trypanosoma cruzi. CD was traditionally endemic to the Americas; however, due to migration it has spread to countries where it is not endemic. The current chemotherapy to treat CD induces several side effects, and its effectiveness in the chronic phase of the disease is controversial. In this contribution, substituted phenylbenzothiazole derivatives were synthesized and biologically evaluated as trypanocidal agents against Trypanosoma cruzi.

Published
2019
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