1. In Vitro Triple Combination of Antifungal Drugs against Clinical Scopulariopsis and Microascus Species.
- Author
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Yao L, Wan Z, Li R, and Yu J
- Subjects
- Antifungal Agents pharmacology, Ascomycota classification, Ascomycota isolation & purification, Caspofungin, Drug Resistance, Multiple, Fungal, Drug Therapy, Combination, Humans, Lipopeptides, Microbial Sensitivity Tests, Mycoses drug therapy, Scopulariopsis classification, Scopulariopsis isolation & purification, Terbinafine, Ascomycota drug effects, Echinocandins pharmacology, Naphthalenes pharmacology, Scopulariopsis drug effects, Triazoles pharmacology
- Abstract
Broth microdilution checkerboard techniques based on the methodology of the Clinical and Laboratory Standards Institute (CLSI) were employed to study the triple antifungal combination of caspofungin, posaconazole, and terbinafine against 27 clinical isolates of Scopulariopsis and Microascus species. Synergy was observed for 26 isolates, whereas antagonism was observed for Scopulariopsis candida in this study., (Copyright © 2015, American Society for Microbiology. All Rights Reserved.)
- Published
- 2015
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