Search

Your search keyword '"G., Snow"' showing total 2 results
Start Over Author "G., Snow" Journal anticancer research
2 results on '"G., Snow"'

1. Perspectives of monoclonal antibodies for detection and treatment of head and neck tumours

Author

J, Quak, M, Gerretsen, R, De Bree, R, Brakenhof, G, Van Dongen, and G, Snow

Subjects
Transplantation, Heterologous, Antibodies, Monoclonal, Mice, Nude, Cell Communication, Mice, Clinical Protocols, Antibody Specificity, Antigens, Neoplasm, Head and Neck Neoplasms, Lymphatic Metastasis, Carcinoma, Squamous Cell, Animals, Humans, Forecasting
Abstract

Monoclonal antibodies (mabs) are potentially powerful tools for the detection and treatment of cancer. To date, only a limited number of mabs are available to head and neck cancer. We produced 5 different groups of mabs to head and neck cancer. These mabs were characterized for their reactivity tumour and non-tumour tissues. Furthermore, biochemical elucidation of recognized antigens was provided. In animal studies the effectiveness of mabs for diagnoses and therapy of cancer is clearly demonstrated. The first results of a clinical study for the detection of head and neck cancer with mabs are shown. Finally, the future of mabs in clinical oncology is discussed.

Published
1993

2. Perspectives of monoclonal antibodies for detection and treatment of head and neck tumours.

Author

Quak J, Gerretsen M, De Bree R, Brakenhof R, Van Dongen G, and Snow G

Subjects
Animals, Antibody Specificity, Antigens, Neoplasm immunology, Carcinoma, Squamous Cell immunology, Carcinoma, Squamous Cell therapy, Cell Communication immunology, Clinical Protocols, Forecasting, Head and Neck Neoplasms immunology, Head and Neck Neoplasms therapy, Humans, Lymphatic Metastasis, Mice, Mice, Nude, Transplantation, Heterologous, Antibodies, Monoclonal therapeutic use, Antigens, Neoplasm analysis, Carcinoma, Squamous Cell diagnosis, Head and Neck Neoplasms diagnosis
Abstract

Monoclonal antibodies (mabs) are potentially powerful tools for the detection and treatment of cancer. To date, only a limited number of mabs are available to head and neck cancer. We produced 5 different groups of mabs to head and neck cancer. These mabs were characterized for their reactivity tumour and non-tumour tissues. Furthermore, biochemical elucidation of recognized antigens was provided. In animal studies the effectiveness of mabs for diagnoses and therapy of cancer is clearly demonstrated. The first results of a clinical study for the detection of head and neck cancer with mabs are shown. Finally, the future of mabs in clinical oncology is discussed.

Published
1993

Catalog

Books, media, physical & digital resources
See catalog results