1. Ivermectin and coagulation: an in vitro study.
- Author
-
Hay J and Arnott MA
- Subjects
- Adult, Dose-Response Relationship, Drug, Humans, In Vitro Techniques, Male, Partial Thromboplastin Time, Prothrombin Time, Thrombin Time, Time Factors, Blood Coagulation drug effects, Ivermectin pharmacology
- Abstract
The prothrombin time, partial thromboplastin time with kaolin, and thrombin clotting time of plasma derived from healthy human volunteers were unaltered after in vitro addition of therapeutic concentrations (20-90 ng ml-1) of ivermectin. No difference in these coagulation tests, relative to untreated controls, was observed after 12 hours' incubation with the drug.
- Published
- 1990
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