1. Translational research on Barrett's esophagus.
- Author
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Baruah A, Buttar N, Chandra R, Chen X, Clemons NJ, Compare D, El-Rifai W, Gu J, Houchen CW, Koh SY, Li W, Nardone G, Phillips WA, Sharma A, Singh I, Upton MP, Vega KJ, and Wu X
- Subjects
- Animals, Barrett Esophagus therapy, Biomarkers, Tumor genetics, Humans, Microsatellite Repeats genetics, Oxidative Stress genetics, Paris, Translational Research, Biomedical trends, Barrett Esophagus diagnosis, Barrett Esophagus genetics, Disease Progression, Translational Research, Biomedical methods
- Abstract
The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on translational research on Barrett's esophagus that address evidence for genetic instability in esophageal cancer; the role of microsatellite instability; the use of histologic and serum Doublecortin-like kinase 1 expression for progression of Barrett's esophagus to adenocarcinoma; the oxidative stress in Barrett's tumorigenesis; the genomic alterations in esophageal cancer; in vivo modeling in Barrett's esophagus; epigenetic and transcriptional regulation in Barrett's esophagus and esophageal adenocarcinoma; and normal and disordered regeneration in Barrett's esophagus., (© 2014 New York Academy of Sciences.)
- Published
- 2014
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