1. Nonalcoholic liver disease: Epidemiology, risk factors, natural history, and management strategies.
- Author
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Agyapong G, Dashti F, and Banini BA
- Subjects
- Humans, United States, Disease Progression, Liver pathology, Risk Factors, Liver Cirrhosis epidemiology, Liver Cirrhosis therapy, Liver Cirrhosis complications, Fibrosis, Non-alcoholic Fatty Liver Disease diagnosis, Non-alcoholic Fatty Liver Disease epidemiology, Non-alcoholic Fatty Liver Disease therapy
- Abstract
Nonalcoholic fatty liver disease (NAFLD) is now the most common chronic liver disease worldwide and a leading indication for liver transplantation in the United States. NAFLD encompasses a heterogeneous clinicopathologic spectrum, ranging from nonalcoholic fatty liver (NAFL) to nonalcoholic steatohepatitis, and progressive fibrosis, which can lead to end-stage liver disease including cirrhosis and hepatocellular cancer. Predictive models suggest that over 100 million adults in the United States will have NAFLD by 2030, representing over a third of the population. In this manuscript, we provide an overview of NAFLD risk factors, natural history (including hepatic and extra-hepatic outcomes), diagnosis, and current management strategies., (© 2023 New York Academy of Sciences.)
- Published
- 2023
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