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Start Over Author "Alomran A" Journal annals of the new york academy of sciences
13 results on '"Alomran A"'

4. IMMUNOSUPPRESSION BY HUMAN ?2-MACROGLOBULIN, A 3800 MrPEPTIDE, AND OTHER DERIVATIVES

Author

William J. Hubbard, George M. Proud, Barry D. Anderson, Andrew E. Balber, Brian K. Shenton, and Alla M. Alomran

Subjects
Immunosuppression Therapy, chemistry.chemical_classification, biology, Chemistry, business.industry, General Neuroscience, medicine.medical_treatment, Carbohydrates, Peptide, Immunosuppression, Pharmacology, Peptide Fragments, General Biochemistry, Genetics and Molecular Biology, Molecular Weight, alpha-2-Macroglobulin, Text mining, History and Philosophy of Science, biology.protein, medicine, Humans, Trypsin, alpha-Macroglobulins, Lymphocytes, business, Cells, Cultured
Published
1983
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5. THE CLINICAL RELEVANCE OF ?2-MACROGLOBULIN

Author

R. M. R. Taylor, G. Proud, P. K. Donnelly, Brian K. Shenton, DavidM.A. Francis, and A. Alomran

Subjects
Text mining, History and Philosophy of Science, business.industry, General Neuroscience, Medicine, Clinical significance, Computational biology, business, General Biochemistry, Genetics and Molecular Biology, Macroglobulin
Published
1983
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6. The clinical relevance of alpha 2-macroglobulin

Author

P K, Donnelly, B K, Shenton, A, Alomran, D M, Francis, G, Proud, and R M, Taylor

Subjects
Immunosuppression Therapy, Liver Cirrhosis, Kinetics, Pancreatitis, Reference Values, Acute Disease, Chronic Disease, Humans, Cholecystectomy, Trypsin, alpha-Macroglobulins, Lymphocytes, Burns, Peptide Hydrolases, Protein Binding
Published
1983

7. A possible mechanism of immunoregulation produced by alpha 2-macroglobulin

Author

G. Proud, A. Alomran, R. M. R. Taylor, Brian K. Shenton, P. K. Donnelly, and DavidM.A. Francis

Subjects
medicine.medical_specialty, Proteases, Erythrocytes, Lymphocyte, Alpha (ethology), Peptide, General Biochemistry, Genetics and Molecular Biology, Arthritis, Rheumatoid, History and Philosophy of Science, Antigen, Reference Values, Internal medicine, Neoplasms, medicine, Humans, Trypsin, alpha-Macroglobulins, Lymphocytes, Uremia, chemistry.chemical_classification, Immunosuppression Therapy, Chemistry, General Neuroscience, Cancer, medicine.disease, Macroglobulin, Endocrinology, medicine.anatomical_structure, Pancreatitis, Acute Disease, Burns
Abstract

Most of the plasma suppressive activity was associated with alpha 2M in both normal subjects and cancer patients. alpha 2M binding to physiological levels of proteases was associated with an increase in the ability to suppress lymphocyte reactivity in the TEEM test. alpha 2M binding to proteases released a peptide that was a component of the alpha 2M; this peptide suppressed lymphocyte reactivity to mitogenic, antigenic, and allogenic stimuli in the TEEM test and in the lymphocyte transformation assay. Physically and biologically similar peptides have been found in the plasma of cancer patients and patients with thermal burns, uremia, and acute pancreatitis.

Published
1983

12. A possible mechanism of immunoregulation produced by alpha 2-macroglobulin.

Author

Alomran A, Shenton BK, Donnelly PK, Francis DM, Proud G, and Taylor RM

Subjects
Acute Disease, Arthritis, Rheumatoid immunology, Burns immunology, Erythrocytes immunology, Humans, Immunosuppression Therapy, Neoplasms immunology, Pancreatitis immunology, Reference Values, Trypsin metabolism, Uremia immunology, alpha-Macroglobulins metabolism, Lymphocytes immunology, alpha-Macroglobulins immunology
Abstract

Most of the plasma suppressive activity was associated with alpha 2M in both normal subjects and cancer patients. alpha 2M binding to physiological levels of proteases was associated with an increase in the ability to suppress lymphocyte reactivity in the TEEM test. alpha 2M binding to proteases released a peptide that was a component of the alpha 2M; this peptide suppressed lymphocyte reactivity to mitogenic, antigenic, and allogenic stimuli in the TEEM test and in the lymphocyte transformation assay. Physically and biologically similar peptides have been found in the plasma of cancer patients and patients with thermal burns, uremia, and acute pancreatitis.

Published
1983
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13. The clinical relevance of alpha 2-macroglobulin.

Author

Donnelly PK, Shenton BK, Alomran A, Francis DM, Proud G, and Taylor RM

Subjects
Acute Disease, Cholecystectomy, Chronic Disease, Humans, Kinetics, Lymphocytes immunology, Peptide Hydrolases metabolism, Protein Binding, Reference Values, Burns blood, Immunosuppression Therapy, Liver Cirrhosis blood, Pancreatitis blood, Trypsin metabolism, alpha-Macroglobulins metabolism
Published
1983
Full Text
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