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Your search keyword '"Adrenal Glands ultrastructure"' showing total 13 results
Start Over Descriptor "Adrenal Glands ultrastructure" Journal annals of the new york academy of sciences
13 results on '"Adrenal Glands ultrastructure"'

1. Age-related effects of dexamethasone administration in adrenal zona reticularis.

Author

Almeida H, Matos L, Ferreira J, and Neves D

Subjects
Adrenal Glands pathology, Adrenal Glands ultrastructure, Animals, Anti-Inflammatory Agents administration & dosage, Apoptosis drug effects, Cell Nucleus pathology, Cell Size, Corticosterone analysis, Corticosterone blood, Dexamethasone administration & dosage, Immunohistochemistry, Male, Random Allocation, Rats, Rats, Wistar, Zona Reticularis pathology, Zona Reticularis ultrastructure, Adrenal Glands drug effects, Aging drug effects, Anti-Inflammatory Agents pharmacology, Dexamethasone pharmacology, Zona Reticularis drug effects
Abstract

Suppression of adrenocorticotropic hormone results in reduced adrenal steroid output, adrenocortical cell atrophy, and apoptosis in young rats. To verify such effects during aging, dexamethasone was injected into rats for 3 days at five different ages; at day 4, adrenals and blood were collected for morphologic and corticosterone assay. Adrenal structure was similar at all ages, but in dexamethasone-injected animals there were ultrastructural features of apoptosis and a higher percentage of TUNEL and caspase-3-labeled nuclei and cytoplasm; their corticosterone decreased significantly. In both groups, there was age-related decrease in the percentage of apoptotic cells, significant only in dexamethasone-injected rats. The data suggest that aged adrenocortical cells are less susceptible to the lack of adrenocorticotropic hormone (ACTH), possibly as a result of their decreased functional ability.

Published
2006
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4. ACTH receptors and the effect of ACTH on adrenal organelles.

Author

Ontjes DA, Ways DK, Mahaffee DD, Zimmerman CF, and Gwynne JT

Subjects
Adenylyl Cyclases metabolism, Adrenal Glands ultrastructure, Animals, Binding Sites, Cell Membrane metabolism, Humans, In Vitro Techniques, Lipoproteins metabolism, Peptide Fragments metabolism, Protein Binding, Adrenal Glands metabolism, Adrenocorticotropic Hormone metabolism, Receptors, Cell Surface
Published
1977
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5. Coupling of H+ gradients to catecholamine transport in chromaffin granules.

Author

Johnson RG, Carty SE, and Scarpa A

Subjects
Adenosine Triphosphate pharmacology, Adrenal Glands ultrastructure, Animals, Biological Transport, Active, Carrier Proteins metabolism, Catecholamine Plasma Membrane Transport Proteins, Cell Membrane Permeability, Cytochrome b Group metabolism, Dopamine metabolism, Dopamine beta-Hydroxylase metabolism, Electrochemistry, Epinephrine metabolism, Humans, Hydrogen-Ion Concentration, Kinetics, Membrane Potentials, Membrane Proteins metabolism, Norepinephrine metabolism, Osmosis, Proton-Translocating ATPases metabolism, Serotonin metabolism, Catecholamines metabolism, Chromaffin Granules metabolism, Chromaffin System metabolism, Membrane Transport Proteins, Protons
Published
1985
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6. Uptake of ascorbic acid by leukocytes.

Author

Moser U

Subjects
Adrenal Glands metabolism, Adrenal Glands ultrastructure, Animals, Ascorbic Acid metabolism, Ascorbic Acid pharmacology, Biological Transport, Active drug effects, Chemotaxis, Leukocyte drug effects, Female, Glucose metabolism, Glucose pharmacology, Granulocytes metabolism, Guinea Pigs, Humans, Kinetics, Lymphocytes metabolism, Male, Monocytes metabolism, N-Formylmethionine Leucyl-Phenylalanine pharmacology, Swine, Ascorbic Acid blood, Leukocytes metabolism
Published
1987
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7. Evidence for direct coupling of proton and anion transport in chromaffin granules.

Author

Pazoles CJ, Creutz CE, and Pollard HB

Subjects
4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid pharmacology, Adenosine Triphosphatases antagonists & inhibitors, Adenosine Triphosphatases metabolism, Adrenal Glands ultrastructure, Animals, Anions, Biological Transport, Cations, Cattle, Chromaffin Granules enzymology, Macromolecular Substances, Chromaffin Granules metabolism, Chromaffin System metabolism, Ion Channels metabolism
Published
1980
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8. The in vivo effect of ACTH on utilization of reducing energy for pregnenolone synthesis by adrenal mitochondria.

Author

Johnson LR, Ruhmann-Wennhold A, and Nelson DH

Subjects
Adrenal Glands ultrastructure, Animals, Electron Transport, Female, Hydroxybutyrates pharmacology, Hypophysectomy, Isocitrates pharmacology, Ketones pharmacology, Kinetics, Malates pharmacology, NADP metabolism, Pregnenolone analysis, Radioimmunoassay, Rats, Stimulation, Chemical, Adrenal Glands metabolism, Adrenocorticotropic Hormone pharmacology, Mitochondria metabolism, Pregnenolone biosynthesis
Published
1973
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9. Lifetime of adrenal cytochrome P-450 as influenced by ACTH.

Author

Purvis JL, Canick JA, Mason JI, Estabrook RW, and McCarthy JL

Subjects
Adrenal Glands ultrastructure, Animals, Chloramphenicol pharmacology, Cytochrome Reductases metabolism, Estrogens pharmacology, Female, Ferredoxins metabolism, Half-Life, Hypophysectomy, Kinetics, Microsomes enzymology, Mitochondria drug effects, Mitochondria ultrastructure, NADP metabolism, Rats, Adrenal Glands enzymology, Adrenocorticotropic Hormone pharmacology, Cytochrome P-450 Enzyme System metabolism, Mitochondria enzymology
Published
1973
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10. Effect of ACTH on adrenal mitochondrial cytochrome P-450 in the rat.

Author

Brownie AC, Alfano J, Jefcoate CR, Orme-Johnson W, Beinert H, and Simpson ER

Subjects
Adrenal Glands ultrastructure, Animals, Chemical Phenomena, Chemistry, Cycloheximide pharmacology, Electron Spin Resonance Spectroscopy, Female, Male, Pregnenolone, Rats, Species Specificity, Stress, Physiological enzymology, Adrenal Glands enzymology, Adrenocorticotropic Hormone, Cytochrome P-450 Enzyme System metabolism, Mitochondria enzymology
Published
1973
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11. Control of substrate flux and adrenal cytochrome P-450.

Author

Bell JJ, Cheng SC, and Harding BW

Subjects
Adrenal Glands ultrastructure, Adrenocorticotropic Hormone pharmacology, Animals, Cattle, Cholesterol analogs & derivatives, Cycloheximide pharmacology, Electron Spin Resonance Spectroscopy, Electron Transport, Microsomes enzymology, Mitochondria drug effects, Mitochondria enzymology, Polyethylene Glycols, Pregnenolone pharmacology, Rats, Adrenal Glands enzymology, Cholesterol metabolism, Cytochrome P-450 Enzyme System metabolism, Desoxycorticosterone metabolism
Published
1973
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12. Drugs, alcohol and sex hormones: a molecular perspective of the receptivity of cytochrome P-450.

Author

Estabrook RW, Mason JI, Baron J, Lambeth D, and Waterman M

Subjects
Adrenal Glands metabolism, Adrenal Glands ultrastructure, Animals, Binding, Competitive, Cattle, Electron Transport, Estradiol metabolism, Hexobarbital metabolism, Microsomes enzymology, Microsomes, Liver enzymology, Mitochondria enzymology, Morphine Derivatives metabolism, NAD metabolism, NADP metabolism, Oxidation-Reduction, Phenobarbital metabolism, Testosterone metabolism, Barbiturates metabolism, Cytochrome P-450 Enzyme System metabolism, Ethanol metabolism, Gonadal Steroid Hormones metabolism
Published
1973
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13. Activator and inhibitor factors in cholesterol side-chain cleavage.

Author

Ungar F, Kan KW, and McCoy KE

Subjects
Adrenal Glands ultrastructure, Animals, Carrier Proteins metabolism, Cattle, Cytochrome P-450 Enzyme System metabolism, Depression, Chemical, Liver metabolism, Microsomes metabolism, Mitochondria metabolism, NADP metabolism, Phospholipids metabolism, Pregnenolone pharmacology, Protein Binding, Serum Albumin, Bovine metabolism, Stimulation, Chemical, Tritium, Adrenal Glands metabolism, Cholesterol metabolism
Published
1973
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