1. Precision medicine in chronic disease management: The multiple sclerosis BioScreen
- Author
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Gourraud, PA, Gourraud, PA, Henry, RG, Cree, BAC, Crane, JC, Lizee, A, Olson, MP, Santaniello, AV, Datta, E, Zhu, AH, Bevan, CJ, Gelfand, JM, Graves, JS, Goodin, DS, Green, AJ, Von Büdingen, HC, Waubant, E, Zamvil, SS, Crabtree-Hartman, E, Nelson, S, Baranzini, SE, Hauser, SL, Gourraud, PA, Gourraud, PA, Henry, RG, Cree, BAC, Crane, JC, Lizee, A, Olson, MP, Santaniello, AV, Datta, E, Zhu, AH, Bevan, CJ, Gelfand, JM, Graves, JS, Goodin, DS, Green, AJ, Von Büdingen, HC, Waubant, E, Zamvil, SS, Crabtree-Hartman, E, Nelson, S, Baranzini, SE, and Hauser, SL
- Abstract
We present a precision medicine application developed for multiple sclerosis (MS): the MS BioScreen. This new tool addresses the challenges of dynamic management of a complex chronic disease; the interaction of clinicians and patients with such a tool illustrates the extent to which translational digital medicine - that is, the application of information technology to medicine - has the potential to radically transform medical practice. We introduce 3 key evolutionary phases in displaying data to health care providers, patients, and researchers: visualization (accessing data), contextualization (understanding the data), and actionable interpretation (real-time use of the data to assist decision making). Together, these form the stepping stones that are expected to accelerate standardization of data across platforms, promote evidence-based medicine, support shared decision making, and ultimately lead to improved outcomes.
- Published
- 2014