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Your search keyword '"Nath, Avindra"' showing total 25 results
Start Over Author "Nath, Avindra" Journal annals of neurology
25 results on '"Nath, Avindra"'

1. Clinicopathology conference: 41‐year‐old woman with chronic relapsing meningitis

Author

Beck, Erin S, Ramachandran, Prashanth S, Khan, Lillian M, Sample, Hannah A, Zorn, Kelsey C, O'Connell, Elise M, Nash, Theodore, Reich, Daniel S, Venkatesan, Arun, DeRisi, Joseph L, Nath, Avindra, and Wilson, Michael R

Subjects
Biomedical and Clinical Sciences, Neurosciences, Clinical Sciences, Adult, Animals, Anticestodal Agents, Arachnoiditis, Cestoda, Cestode Infections, Chronic Disease, Diagnosis, Differential, Female, Humans, Lumbar Vertebrae, Meningitis, Bacterial, Mycobacterium tuberculosis, Recurrence, Neurology & Neurosurgery, Clinical sciences
Published
2019

2. White and Gray Matter Changes are Associated With Neurocognitive Decline in HIV Infection.

Author

Chien, Alice, Wu, Tianxia, Lau, Chuen‐Yen, Pandya, Darshan, Wiebold, Amanda, Agan, Brian, Snow, Joseph, Smith, Bryan, Nath, Avindra, and Nair, Govind

Subjects
GRAY matter (Nerve tissue), HIV infections, WHITE matter (Nerve tissue), MAGNETIC resonance imaging, EXECUTIVE function
Abstract

Objective: To investigate the relationship between neurocognitive deficits and structural changes on brain magnetic resonance imaging in people living with HIV (PLWH) with good virological control on combination antiretroviral therapy, compared with socioeconomically matched control participants recruited from the same communities. Methods: Brain magnetic resonance imaging scans, and clinical and neuropsychological data were obtained from virologically controlled PLWH (viral load of <50 c/mL and at least 1 year of combination antiretroviral therapy) and socioeconomically matched control participants. Magnetic resonance imaging was carried out on 3 T scanner with 8‐channel head coils and segmented using Classification using Derivative‐based Features. Multiple regression analysis was performed to examine the association between brain volume and various clinical and neuropsychiatric parameters adjusting for age, race, and sex. To evaluate longitudinal changes in brain volumes, a random coefficient model was used to evaluate the changes over time (age) adjusting for sex and race. Results: The cross‐sectional study included 164 PLWH and 51 controls, and the longitudinal study included 68 PLWH and 20 controls with 2 or more visits (mean 2.2 years, range 0.8–5.1 years). Gray matter (GM) atrophy rate was significantly higher in PLWH compared with control participants, and importantly, the GM and global atrophy was associated with the various neuropsychological domain scores. Higher volume of white matter hyperintensities were associated with increased atherosclerotic cardiovascular disease risk score, and decreased executive functioning and memory domain scores in PLWH. Interpretation: These findings suggest ongoing neurological damage even in virologically controlled participants, with significant implications for clinical management of PLWH. ANN NEUROL 2024;95:941–950 [ABSTRACT FROM AUTHOR]

Published
2024
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3. Experimental Neurotherapeutics: Surfing the Tidal Wave of New Opportunities

Author

Reoma, Lauren B., primary, Busza, Ania, additional, Mouradian, M. Maral, additional, Kaufmann, Petra, additional, Augustine, Erika F., additional, Frank, Samuel, additional, Sutula, Thomas P., additional, Cole, Andrew J., additional, Fitter, Heather D., additional, Meurer, William, additional, Nath, Avindra, additional, and Griggs, Robert C., additional

Published
2023
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4. Antibody Response to HML‐2 May Be Protective in Amyotrophic Lateral Sclerosis

Author

Garcia‐Montojo, Marta, primary, Simula, Elena Rita, additional, Fathi, Saeed, additional, McMahan, Cynthia, additional, Ghosal, Anubrata, additional, Berry, James D., additional, Cudkowicz, Merit, additional, Elkahloun, Abdel, additional, Johnson, Kory, additional, Norato, Gina, additional, Jensen, Peter, additional, James, Tony, additional, Sechi, Leonardo A., additional, and Nath, Avindra, additional

Published
2022
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5. Human Endogenous Retrovirus K Envelope in Spinal Fluid of Amyotrophic Lateral Sclerosis Is Toxic

Author

Steiner, Joseph P., primary, Bachani, Muzna, additional, Malik, Nasir, additional, DeMarino, Catherine, additional, Li, Wenxue, additional, Sampson, Kevon, additional, Lee, Myoung‐Hwa, additional, Kowalak, Jeffery, additional, Bhaskar, Manju, additional, Doucet‐O'Hare, Tara, additional, Garcia‐Montojo, Marta, additional, Cowen, Maria, additional, Smith, Bryan, additional, Reoma, Lauren Bowen, additional, Medina, Julie, additional, Brunel, Joanna, additional, Pierquin, Justine, additional, Charvet, Benjamin, additional, Perron, Hervé, additional, and Nath, Avindra, additional

Published
2022
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7. Strengthened through Diversity: A Blueprint for Organizational Change

Author

Willis, Allison, primary, Skolarus, Lesli E., additional, Faigle, Roland, additional, Menon, Uma, additional, Redwine, Hannah, additional, Brown, Amanda M., additional, Felton, Elizabeth, additional, Mendizabal, Adys, additional, Nath, Avindra, additional, Jensen, Frances, additional, and McArthur, Justin C., additional

Published
2021
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13. Paramagnetic Rim Lesions are Specific to Multiple Sclerosis: An International Multicenter 3T MRI Study

Author

Maggi, Pietro, primary, Sati, Pascal, additional, Nair, Govind, additional, Cortese, Irene C. M., additional, Jacobson, Steven, additional, Smith, Bryan R., additional, Nath, Avindra, additional, Ohayon, Joan, additional, Pesch, Vincent, additional, Perrotta, Gaetano, additional, Pot, Caroline, additional, Théaudin, Marie, additional, Martinelli, Vittorio, additional, Scotti, Roberta, additional, Wu, Tianxia, additional, Du Pasquier, Renaud, additional, Calabresi, Peter A., additional, Filippi, Massimo, additional, Reich, Daniel S., additional, and Absinta, Martina, additional

Published
2020
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14. Fatal encephalopathy with wild‐type JC virus and ruxolitinib therapy

Author

Reoma, Lauren Bowen, primary, Trindade, Christopher Julius, additional, Monaco, Maria Chiara, additional, Solis, Jamie, additional, Montojo, Marta Garcia, additional, Vu, Phuong, additional, Johnson, Kory, additional, Beck, Erin, additional, Nair, Govind, additional, Khan, Omar I., additional, Quezado, Marta, additional, Hewitt, Stephen M., additional, Reich, Daniel S., additional, Childs, Richard, additional, and Nath, Avindra, additional

Published
2019
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15. Chronic Dengue Virus Panencephalitis in a Patient with Progressive Dementia with Extrapyramidal Features

Author

Johnson, Tory P., primary, Larman, H. Benjamin, additional, Lee, Myoung‐Hwa, additional, Whitehead, Stephen S., additional, Kowalak, Jeffrey, additional, Toro, Camilo, additional, Lau, C. Christopher, additional, Kim, Juyun, additional, Johnson, Kory R., additional, Reoma, Lauren B., additional, Faustin, Arline, additional, Pardo, Carlos A., additional, Kottapalli, Sanjay, additional, Howard, Jonathan, additional, Monaco, Daniel, additional, Weisfeld‐Adams, James, additional, Blackstone, Craig, additional, Galetta, Steven, additional, Snuderl, Matija, additional, Gahl, William A., additional, Kister, Ilya, additional, and Nath, Avindra, additional

Published
2019
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16. Reply

Author

Wheeler, David, primary, Jelinek, Christine, additional, Anderson, Carol, additional, Gundry, Rebekah, additional, Irani, David, additional, Calabresi, Peter, additional, Cotter, Robert, additional, and Nath, Avindra, additional

Published
2007
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25. Paramagnetic Rim Lesions are Specific to Multiple Sclerosis: An International Multicenter 3T MRI Study

Author

Steven Jacobson, Tianxia Wu, Avindra Nath, Pascal Sati, Vincent Van Pesch, Daniel S. Reich, Marie Théaudin, Irene Cortese, Caroline Pot, Massimo Filippi, Vittorio Martinelli, Peter A. Calabresi, Renaud Du Pasquier, M. Absinta, Pietro Maggi, Govind Nair, Roberta Scotti, Gaetano Perrotta, Bryan Smith, Joan Ohayon, UCL - SSS/IONS/CEMO - Pôle Cellulaire et moléculaire, UCL - (SLuc) Service de neurologie, Maggi, Pietro, Sati, Pascal, Nair, Govind, Cortese, Irene C M, Jacobson, Steven, Smith, Bryan R, Nath, Avindra, Ohayon, Joan, van Pesch, Vincent, Perrotta, Gaetano, Pot, Caroline, Théaudin, Marie, Martinelli, Vittorio, Scotti, Roberta, Wu, Tianxia, Du Pasquier, Renaud, Calabresi, Peter A, Filippi, Massimo, Reich, Daniel S, and Absinta, Martina

Subjects
Adult, Male, 0301 basic medicine, Pathology, medicine.medical_specialty, Multiple Sclerosis, Neuroimaging, Sensitivity and Specificity, Article, Diagnosis, Differential, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Prevalence, medicine, Humans, Diagnostic biomarker, Aged, Retrospective Studies, medicine.diagnostic_test, Chronic Active, business.industry, Multiple sclerosis, Magnetic resonance imaging, Middle Aged, medicine.disease, Clinical disease, Magnetic Resonance Imaging, Hyperintensity, 030104 developmental biology, Neurology, Female, Neurology (clinical), Nervous System Diseases, Differential diagnosis, business, 030217 neurology & neurosurgery
Abstract

In multiple sclerosis (MS), a subset of chronic active white matter lesions are identifiable on magnetic resonance imaging by their paramagnetic rims, and increasing evidence supports their association with severity of clinical disease. We studied their potential role in differential diagnosis, screening an international multicenter clinical research-based sample of 438 individuals affected by different neurological conditions (MS, other inflammatory, infectious, and non-inflammatory conditions). Paramagnetic rim lesions, rare in other neurological conditions (52% of MS vs 7% of non-MS cases), yielded high specificity (93%) in differentiating MS from non-MS. Future prospective multicenter studies should validate their role as a diagnostic biomarker. ANN NEUROL 2020;88:1034-1042.

Published
2020

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