1. Voxel-based morphometric magnetic resonance imaging (MRI) postprocessing in MRI-negative epilepsies
- Author
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Andreas V. Alexopoulos, Imad Najm, Stephen E. Jones, William Bingaman, Zeenat Jaisani, Z. Irene Wang, Richard A. Prayson, Chong H. Wong, Jorge Gonzalez-Martinez, Aleksandar J. Ristić, Richard C. Burgess, and Balu Krishnan
- Subjects
Pathology ,medicine.medical_specialty ,medicine.diagnostic_test ,Extramural ,Mri negative ,business.industry ,Retrospective cohort study ,Magnetic resonance imaging ,Outcome assessment ,medicine.disease ,computer.software_genre ,Epilepsy ,Neurology ,Morphometric analysis ,Voxel ,medicine ,Neurology (clinical) ,Radiology ,business ,computer - Abstract
Objective In the presurgical workup of MRI-negative (MRI−, or “nonlesional”) pharmacoresistant focal epilepsy (PFE) patients, discovering a previously undetected lesion can drastically change the evaluation and likely improve surgical outcome. Our study utilizes a voxel-based MRI post-processing technique, implemented in a morphometric analysis program (MAP), to facilitate detection of subtle abnormalities in a consecutive cohort of MRI− surgical candidates.
- Published
- 2015