1. Plasma Lipid Levels in Relation to Disease Severity in Sickle Cell Anaemia in Abakaliki, Southeast Nigeria
- Author
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Nnachi OC, Edenya OO, Okoye HC, Akpa CO, Nwani FO, and Nwani EI
- Subjects
cholesterol ,haemoglobinopathy ,high-density lipoprotein-cholesterol ,sickle cell disease ,total cholesterol ,Medicine (General) ,R5-920 ,Public aspects of medicine ,RA1-1270 - Abstract
Background: Dyslipidaemia has been implicated in the pathophysiology of sickle cell disease (SCD) complications; hence its role requires further elucidation. Objectives: To investigate the relationship between disease severity and plasma lipid levels of patients with sickle cell anaemia. Methods: A cross-sectional study design was used for the survey. A total of 50 patients with sickle cell anaemia and 50 controls without SCD were recruited for the study. The clinical data and plasma lipid levels of lipids and haemoglobin parameters were analysed. Results: The majority of the participants were aged 18-25 years. Total plasma cholesterol and HDL-C were significantly lower in individuals with SCA compared with the controls (3.3±1.2 vs 4.2±1.2; p
- Published
- 2023
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