To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.annemergmed.2007.04.015 Byline: Philip B. Dattilo (a), Susan M. Hailpern (b), Kerrie Fearon (a), Davendra Sohal (a), Charles Nordin (a) Abstract: [beta]-Blocker use is associated with coronary artery spasm after cocaine administration but also decreases mortality in patients with myocardial infarction or systolic dysfunction. We conduct a retrospective cohort study to analyze the safety of [beta]-blockers in patients with positive urine toxicology results for cocaine. Author Affiliation: (a) Department of Medicine, Jacobi Medical Center, Bronx, NY (b) Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY. Article History: Received 19 December 2006; Revised 8 March 2007; Revised 4 April 2007; Accepted 13 April 2007 Article Note: (footnote) Supervising editor: Richard C. Dart, MD, PhD Author contributions: PBD and DS conceived the study. PBD and KF collected the data. CN and SMH developed the strategy for data analysis. CN, PBD, DS, and SMH analyzed the data. SMH, PBD, and CN interpreted the data. CN and SMH drafted the article; CN, SMH, and PBD contributed to its revision. CN takes responsibility for the paper as a whole. Funding and support: By Annals policy, all authors are required to disclose any and all commercial, financial, and other relationships in any way related to the subject of this article, that might create any potential conflict of interest. The authors have stated that no such relationships exist. See the Manuscript Submission Agreement in this issue for examples of specific conflicts covered by this statement. Publication dates: Available online June 20, 2007. Earn CME Credit: Continuing Medical Education for this article is available at: www.ACEP-EMedHome.com.