1. Lymphocyte subsets in kala-azar.
- Author
-
Sciotto A, Russo-Mancuso G, Zinna CM, Comisi FF, Sciannaca RM, and Schiliro G
- Subjects
- Anemia etiology, Antibodies, Protozoan analysis, Antigens, CD analysis, CD4 Antigens analysis, Child, Preschool, Humans, Immunoglobulins analysis, Leishmaniasis, Visceral blood, Leishmaniasis, Visceral complications, Leukopenia etiology, Time Factors, Leishmaniasis, Visceral immunology, Lymphocytes immunology
- Abstract
We examined lymphocyte subsets in peripheral blood from children with visceral leishmaniasis both in the active stage of the disease and after recovery. At diagnosis, CD2+ and CD4+ cells showed a significant decrease while CD8+ cells were significantly increased when compared with controls; CD4/CD8 ratio was inverted. All of these alterations returned to normal values 3 months after recovery.
- Published
- 1989