1. Klebsiella pneumoniae C3 lipopolysaccharide mutants obtained by resistance to bacteriophage FC3-9
- Author
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Vicente J. Benedí, Juan Jofre, and Juan M. Tomás
- Subjects
Lipopolysaccharides ,Antigens, Bacterial ,Lipopolysaccharide ,biology ,Klebsiella pneumoniae ,Mutant ,General Medicine ,biology.organism_classification ,Enterobacteriaceae ,Microbiology ,Bacteriophage ,chemistry.chemical_compound ,chemistry ,Antigen ,Mutation ,Bacteriophages ,Bacterial outer membrane ,Bacteria ,Bacterial Outer Membrane Proteins - Abstract
Bacteriophage FC3-9 is one of the several bacteriophages of Klebsiella pneumoniae C3 isolated in our laboratory. Mutants resistant to this bacteriophage were isolated and found to be devoid of lipopolysaccharide O antigen, modified in outer-membrane protein composition and sensitive to complement killing (serum-sensitive), unlike the wild-type strain. Serum-resistant mutants were isolated from these strains. They regained the lipopolysaccharide O antigen and the wild-type outer membrane protein composition and became sensitive to bacteriophage FC3-9.
- Published
- 1986
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