1. Unexpected migration of free light chains in urinary protein electrophoresis.
- Author
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Nel I, Thiolières JM, Ghillani-Dalbin P, Jacquiaud C, and Piéroni L
- Subjects
- Aged, Diagnosis, Differential, Diagnostic Errors, Electrophoresis, Female, Humans, Male, Middle Aged, Monoclonal Gammopathy of Undetermined Significance diagnosis, Monoclonal Gammopathy of Undetermined Significance urine, Multiple Myeloma diagnosis, Proteinuria urine, Immunoglobulin Light Chains urine, Immunoglobulin kappa-Chains urine, Multiple Myeloma urine, Proteinuria diagnosis, Urinalysis methods
- Abstract
Urinary protein electrophoresis analysis (UPE) is an essential investigation for the study of abnormal proteins in urines. The interpretation of this analysis must be comprehensive and relevant. Indeed, UPE is often requested by clinicians and may have an important impact in patient's management. This paper presents two cases with free light chains showing unexpected electrophoretic migration which can lead to the misinterpretation of results. This article helps biologists to keep in mind the interest of UPE among the several analyses useful in the laboratory.
- Published
- 2017
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