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Simple Summary: Normal values of tear production (STT) and intraocular pressure (IOP) are important values resulting from ophthalmic examinations in animals, but so far there are no data from conscious red deer. The establishment of reference value ranges specific to conscious animals may be useful to institutions in settings where chemical immobilization is not necessary for the examination of the species. A total of 60 red deer were examined in this study. Both eyes of all red deer underwent a complete ophthalmic examination, including evaluation of tear production with the Schirmer tear test and IOP readings. The mean ± standard deviation of STT values were 18.35 ± 4.54 mm/30 s in the right eye and 17.87 ± 4.12 mm/30 s in the left; for both eyes, 18.11 ± 4.33 mm/30 s, with a reference range of 17.33–18.89 mm/30 s. IOP was as follows: 26.96 ± 4.42 mmHg in the right eye and 26.67 ± 3.80 mmHg in the left; for both eyes, 26.81 ± 4.11 mmHg, with a reference range of 26.07–27.55 mm/30 s. No statistically significant differences were found between the right and left eye in terms of IOP and STT values. This study provides the normal range for STT and IOP in healthy red deer. It demonstrates that STT is a practical method for determining tear production, and rebound tonometry is a practical method for evaluating IOP in ophthalmic examinations of deer. Normal values of tear production (STT) and intraocular pressure (IOP) have not been reported in conscious red deer to date. The objective was to determine the normal range of STT and IOP in clinically healthy, conscious red deer (Cervus elaphus) by utilizing a chute restraint. A total of 60 red deer were examined in this study. Both eyes of all red deer underwent a complete ophthalmic examination, including evaluation of tear production with the Schirmer tear test (STT) and assessment of intraocular pressure (IOP) with rebound tonometry, employing the TonoVet® device. The mean ± standard deviation of STT values were 18.35 ± 4.54 mm/30 s in the right eye and 17.87 ± 4.12 mm/30 s in the left; for both eyes, 18.11 ± 4.33 mm/30 s, with a reference range of 17.33–18.89 mm/30 s. IOP was as follows: 26.96 ± 4.42 mmHg in the right eye and 26.67 ± 3.80 mmHg in the left; for both eyes, it was 26.81 ± 4.11 mmHg, with a reference range of 26.07–27.55 mm/30 s. No statistically significant differences were observed between the IOP and STT values of the right and left eyes. This study provides a reference range for the STT and IOP in healthy red deer, showing that STT determination of tear production, and rebound tonometry to evaluate the IOP methods, are practical methods for ophthalmic examination in deer. [ABSTRACT FROM AUTHOR]

Simple Summary: In veterinary medicine, the use of sedative agents to perform clinical and diagnostic procedures is increasingly common. Several anesthetic drugs decrease tear flow production. In recent years, interest in the clinical efficacy of sedative and hypnotic agents for new and atraumatic routes of administration has increased. Tear film production has never been investigated in cats who received sedative agents by the intrarectal route (IR). The aim of this study is to compare the clinical effects of a mixture of dexmedetomidine, ketamine and midazolam on tear film flow administered by the IR versus the intramuscular route (IM). Cats are often easily stressed and uncooperative. The use of sedative agents in the feline species is widely used to perform even minor clinical and diagnostic procedures. The aim of this study is to assess the impact on tear film production of the intrarectal route (IR) administration of a mixture of dexmedetomidine, ketamine and midazolam in comparison with the intramuscular (IM) one. A group of twenty cats were involved in a randomized and blinded clinical trial. A clinical and ophthalmological examination was conducted on the cats. The IR group received dexmedetomidine 0.003 mg kg−1, ketamine 4 mg kg−1 and midazolam 0.4 mg kg−1; the IM group received dexmedetomidine 0.003 mg kg−1, ketamine 2 mg kg−1 and midazolam 0.2 mg kg−1. A Shirmer tear test I (STT- I) was conducted 1 h before sedation and 2′, 10′, 20′, 30′, 40′, and 80′ post drug administration. The reaction to STT-I administration was also evaluated. The IM group has a lower mean tear production than the IR group for all time points evaluated. Cats in the IM group showed less reaction to STT-I administration. This study may suggest that the effect of sedative agents administered by the IR route has a lower incidence on tear production than the IM one. The use of eye lubricant is recommended in any case. [ABSTRACT FROM AUTHOR]

Simple Summary: Different sedatives and anesthetic drugs have been reported to cause adverse ocular side effects, such as an exposure keratopathy due to loss of eyelid reflex, lagophthalmos, reduced stability of the tear film and decreased basal tear production. In the present study, the effects of two sedation protocols, acepromazine (ACP) and acepromazine–methadone (ACP–MET) combination, on tear production measured by the Schirmer Tear Test (STT) 1 on canine eyes were investigated, hypothesizing that both sedation protocols cause a reduction in canine tear production for a variable time. A significant decrease in tear production until 2 h after drug administration compared to basal tear values was observed in the ACP experimental protocol, while in the ACP + MET protocol, this reduction persisted until 8 h. In the ACP + MET group, after 40 min, 100% of dogs showed STT 1 readings lower than 15 mm/min, which could predispose them to corneal injuries. The major reduction in tear production due to the ACP + MET protocol proves the need for adequate corneal hydration, particularly to discourage its use in animals with altered tear production. The purpose of the current study was to investigate the effects of two commonly used sedation protocols in dogs, acepromazine (ACP) and acepromazine–methadone (ACP–MET) combination, on tear production measured by the Schirmer Tear Test (STT) 1. We hypothesized that both sedation protocols cause a reduction in canine tear production for a variable time. Fifteen client-owned dogs were recruited for the study. Each dog was subjected to sedation twice, 2–3 weeks apart, and they were randomly allocated to one of two groups receiving ACP (0.015 mg kg−1) or ACP–MET (0.010 mg kg−1 and 0.2 mg kg−1) intramuscularly. In both eyes, tear production was measured 15 min before sedation (T0) and 20 min (T20 m), 40 min (T40 m), 1 h (T1), 2 h (T2), 4 h (T4) and 8 h (T8), after drug administration. Two-way repeated measures ANOVA, followed by the Bonferroni post hoc test (p < 0.05), showed a significant effect of time (p < 0.0001) and treatment (p < 0.0001). A significant decrease in tear production at T20 m, T40 m, T1 and T2 compared to T0 was observed in the ACP experimental protocol, while in the ACP + MET protocol, this reduction persisted until T8. Comparing the two experimental protocols, no statistically significant differences were observed at T0 or T20 m, and STT 1 values were statistically lower in the ACP + MET than the ACP protocol at the other data points. In the ACP + MET group, at T40 m, 100% of dogs showed STT 1 readings lower than 15 mm/min. This finding is clinically relevant as it can predispose dogs to corneal injuries. The major reduction in tear production due to the ACP + MET protocol proves the need for adequate corneal hydration, particularly to discourage its use in animals with altered tear production. The data obtained provide important information helping clinicians to better manage the drug's effects on tear production. [ABSTRACT FROM AUTHOR]

Simple Summary: In Italy, chickens are used for egg production and as courtyard/domestic animals and consequently veterinarians need to know their general and specialist characteristics. One key area is normal ocular measurements in order to understand any pathological changes affecting the eyes. For an accurate diagnosis and better management of ophthalmic diseases in chickens, this paper describes the normal values for the evaluation of ocular tear production, intraocular pressure, and biometric measurements of the eyes and on the microbial and cultural flora normally present in the conjunctival sac in two Italian chicken breeds. Given the abundance of chickens in Italy, it is important for veterinarians to know the normal state of chickens' eyes in order to identify any ophthalmic pathological changes. The aim of this study was to determine the normal values of select ocular parameters and to evaluate conjunctival microflora in two Italian chicken breeds. Sixty-six healthy chickens underwent a complete ophthalmic examination, which included a phenol red thread test (PRTT) for the evaluation of tear production and the assessment of intraocular pressure by rebound tonometry. B-mode ultrasound biometric measurements and conjunctival microflora identification were also performed in twenty-seven chickens. Mean PRTT was 23.77 ± 2.99 mm/15 s in the Livorno breed and 19.95 ± 2.81 mm/15 s in the Siciliana breed. Mean intraocular pressure was 14.3 ± 1.17 mmHg in the Livorno breed and 14.06 ± 1.15 mmHg in the Siciliana breed. Reference ranges for morphometric parameters were reported in the two breeds. Twenty-three chickens (85.18%) were bacteriologically positive. Chlamydia spp. antigen was detected in 14.81% of chickens. No positive cultures were obtained for fungi. Normal reference range values for selected ophthalmic parameters were obtained in clinically healthy chickens, which could facilitate accurate diagnosis and better management of ophthalmic diseases in these animals. [ABSTRACT FROM AUTHOR]