1. Cardiovascular and Venous Thromboembolic Events After Hospital Discharge for COVID-19: A Prospective Single Center Study.
- Author
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Soudet, S., Basille, D., Carette, H., Mercier, M., Andrejak, C., and Sevestre, M.-A.
- Subjects
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THROMBOEMBOLISM risk factors , *RISK assessment , *MYOCARDIAL infarction , *DOPPLER ultrasonography , *ACADEMIC medical centers , *MAJOR adverse cardiovascular events , *VEINS , *SCIENTIFIC observation , *PERIPHERAL vascular diseases , *DISCHARGE planning , *MULTIVARIATE analysis , *DESCRIPTIVE statistics , *DISEASES , *LONGITUDINAL method , *ODDS ratio , *THROMBOEMBOLISM , *CONFIDENCE intervals , *COVID-19 , *THROMBOSIS , *DISEASE risk factors ,MORTALITY risk factors - Abstract
Coronavirus disease 2019 (COVID-19) is associated with an increase in venous thrombotic and cardiovascular (CV) events has been reported during hospitalization. No systematic ultrasound follow-up to evaluate sequelae was ever that took place carried out prospectively associated with the evaluation of CV morbidity-mortality at 3 months post-discharge. Consecutive patients hospitalized for COVID-19 in the Amiens-Picardie University Hospital between 1st February and 31st August 2020 were included. The primary objective was the thrombosis incidence at 3 months after hospital discharge. Thrombosis was defined as either venous thromboembolism (VTE) or a CV event (CVE: myocardial infarction (MI), stroke or peripheral arterial disease). A secondary objective was to determine the risk factors for thrombotic events. We included 498 patients (279 men; 56%) of median age 66 (55-76) years. The primary composite outcome occurred in 27 patients (5.4%); 19 patients (3.8%) presented a CVE (stroke, n = 5; MI, n = 9; and peripheral arterial disease, n = 5). Two patients (0.8%) presented VTE. Six patients (1.2%) died. In multivariate analysis, a previous CVE was associated with thrombosis (OR 3.11; 95% CI 1.17-8.24). COVID-19 was significantly associated with thrombotic events post hospital discharge. Special attention should be given to CVE in the follow-up of patients with a previous thrombotic event. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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