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Competing Interests: Die Autoren erklären, dass keine Interessenkonflikte vorliegen.

Competing Interests: Die Autoren erklären, dass keine Interessenkonflikte vorliegen.

In contrast to ketones and carboxylic esters, amides are classically seen as comparatively unreactive members of the carbonyl family, owing to their unique structural and electronic features. However, recent decades have seen the emergence of research programmes focused on the selective activation of amides under mild conditions. In the past four years, this area has continued to rapidly develop, with new advances coming in at a fast pace. Several novel activation strategies have been demonstrated as effective tools for selective amide activation, enabling transformations that are at once synthetically useful and mechanistically intriguing. This Minireview comprises recent advances in the field, highlighting new trends and breakthroughs in what could be called a new age of amide activation., Competing Interests: The authors declare no conflict of interest., (© 2022 The Authors. Angewandte Chemie published by Wiley-VCH GmbH.)

Competing Interests: Die Autoren erklären, dass keine Interessenkonflikte vorliegen.

Competing Interests: Die Autoren erklären, dass keine Interessenkonflikte vorliegen.

Competing Interests: Die Autoren erklären, dass keine Interessenkonflikte vorliegen.

Competing Interests: Die Autoren erklären, dass keine Interessenkonflikte vorliegen.