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Reported herein, for the first time, is the selective ruthenium-catalyzed reductive alkoxylation and amination of phthalimides/succinimides. Notably, this novel methodology avoids hydrogenation of the aromatic ring and allows methoxylation of substituted imides with good to excellent selectivity for one of the carbonyl groups. The reported method opens the door to the development of new processes for the selective synthesis of various functionalized N-heterocyclic compounds. As an example, intramolecular reductive couplings to afford tricyclic compounds are presented for the first time. [ABSTRACT FROM AUTHOR]

The article discusses the importance of selective methylation of amines with carbon dioxide (CO2) and hydrogen (H2) in the construction of organic compounds in nature. It states the developments of thermodynamically stable carbon dioxide (CO2) molecules which formates into methanol and methane. It also emphasizes on the developments of efficient methylation methods which uses bioactive compounds to create chemicals.

The article discusses the importance of selective methylation of amines with carbon dioxide (CO2) and hydrogen (H2) in the construction of organic compounds in nature. It states the developments of thermodynamically stable carbon dioxide (CO2) molecules which formates into methanol and methane. It also emphasizes on the developments of efficient methylation methods which uses bioactive compounds to create chemicals.