1. A Labeled Neutral Endopeptidase Inhibitor as a Potential Tool for Tumor Diagnosis and Prognosis
- Author
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Anne Gruaz-Guyon, André Pèlegrin, Anthony Romieu, Olivier Raguin, Marie-Claude Fournie-Zaluski, Jacques Barbet, Didier Pélaprat, Bernard P. Roques, and François Chatelet
- Subjects
Tumor targeting ,Peptidomimetic ,Binding, Competitive ,Models, Biological ,Catalysis ,Mice ,Text mining ,Cell Line, Tumor ,Neoplasms ,Animals ,Humans ,Protease Inhibitors ,Receptor ,Neprilysin ,Aspartic Acid ,Mice, Inbred BALB C ,Binding Sites ,Molecular Structure ,Chemistry ,business.industry ,General Medicine ,General Chemistry ,Prognosis ,Phosphinic Acids ,Biochemistry ,business - Abstract
F-FDG) have greatly improved the diag-nosis and staging of numerous tumors with somatostatin-receptor-subtype overexpression or active glucose metabo-lism,respectively.Thisentailedthedevelopmentofnumerousradiolabeled peptides that target other receptors overex-pressed by tumors that do not accumulate somatostatinanalogues or
- Published
- 2005
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