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Your search keyword '"kemiallinen synteesi"' showing total 2 results
Start Over Descriptor "kemiallinen synteesi" Journal angewandte chemie (international ed. in english)
2 results on '"kemiallinen synteesi"'

1. Controlling Oxidative Addition and Reductive Elimination at Tin(I) via Hemi-Lability

Author

Nicholas H. Rees, Agamemnon E. Crumpton, Petra Vasko, Simon Aldridge, Jamie Hicks, Caitilín McManus, and Alexa Caise

Subjects
oxidative addition, chemistry.chemical_element, 010402 general chemistry, 01 natural sciences, Catalysis, Dissociation (chemistry), Reductive elimination, reversibility, Nucleophilic aromatic substitution, tin, Polymer chemistry, Pincer ligand, kemiallinen synteesi, Chemistry, 010405 organic chemistry, reductive elimination, ligandit, kompleksiyhdisteet, General Chemistry, General Medicine, Acceptor, Oxidative addition, 3. Good health, 0104 chemical sciences, hemi-labile ligand, orgaaniset tinayhdisteet, tina, Amine gas treating, Tin
Abstract

We report on the synthesis of a distannyne supported by a pincer ligand bearing pendant amine donors that is capable of reversibly activating E–H bonds at one or both of the tin centres through dissociation of the hemi-labile N–Sn donor/acceptor interactions. This chemistry can be exploited to sequentially (and reversibly) assemble mixed-valence chains of tin atoms of the type ArSn{Sn(Ar)H} n SnAr ( n = 1, 2). The experimentally observed (decreasing) propensity towards chain growth with increasing chain length can be rationalized both thermodynamically and kinetically by the electron-withdrawing properties of the –Sn(Ar)H– backbone units generated via oxidative addition. peerReviewed

Published
2021

2. Control of N-Heterocyclic Carbene Catalyzed Reactions of Enals: Asymmetric Synthesis of Oxindole-γ-Amino Acid Derivatives

Author

Qiang Liu, Sun Li, Kari Rissanen, Xiang-Yu Chen, Jiawen Xiong, He Sheng, Dieter Enders, and Carolina von Essen

Subjects
Stereochemistry, Substituent, 010402 general chemistry, 01 natural sciences, Catalysis, Stereocenter, chemistry.chemical_compound, aldehydit, aldehydes, Phenyl group, Oxindole, ta116, orgaaniset yhdisteet, kemiallinen synteesi, 010405 organic chemistry, Enantioselective synthesis, General Medicine, General Chemistry, Cycloaddition, 0104 chemical sciences, chemistry, organic compounds, Carbene, chemical synthesis
Abstract

A strategy to control the switch between a non‐cycloaddition reaction and a cycloaddition reaction of enals, using N‐heterocyclic carbene (NHC) catalyisis, has been developed. The new scalable protocol leads to γ‐amino‐acid esters bearing a tetrasubstituted stereocenter in good yields and high stereoselectivities by homo‐Mannich reactions of enals and isatin‐derived ketimines. By simply changing the N‐ketimine substituent to an ortho‐hydroxy phenyl group, the corresponding spirocyclic oxindolo‐γ‐lactams are obtained. peerReviewed

Published
2017

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