1. Anesthetic management of a parturient with hyperhomocysteinemia.
- Author
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Luzardo GE, Karlnoski RA, Williams B, Mangar D, and Camporesi EM
- Subjects
- Adult, Anesthetics, Inhalation adverse effects, Blood Coagulation Tests, Blood Loss, Surgical, Drug Administration Schedule, Enoxaparin administration & dosage, Female, Heparin administration & dosage, Humans, Hyperhomocysteinemia blood, Live Birth, Nitrous Oxide adverse effects, Pregnancy, Pregnancy Complications, Hematologic blood, Anesthesia, Spinal, Anticoagulants administration & dosage, Blood Coagulation drug effects, Cesarean Section, Homocysteine blood, Hyperhomocysteinemia drug therapy, Parturition blood, Pregnancy Complications, Hematologic drug therapy
- Abstract
High plasma levels of homocysteine are associated with an increased risk for thromboembolic events. Neuraxial anesthesia techniques may be relatively contraindicated in anticoagulated patients, and nitrous oxide may exacerbate the condition by inhibiting the conversion of homocysteine to methionine. We describe the anesthetic implications and management of a patient with hyperhomocysteinemia undergoing an nonemergent cesarean delivery.
- Published
- 2008
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