4 results on '"Ellen, Wang"'
Search Results
2. Incidence of and Factors Associated With Prolonged and Persistent Postoperative Opioid Use in Children 0–18 Years of Age
- Author
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T. Anthony Anderson, Ellen Wang, Eric C. Sun, Elizabeth De Souza, Andrew Ward, Nicholas Bambos, and Daniel Miller
- Subjects
Male ,Pediatrics ,medicine.medical_specialty ,Adolescent ,Logistic regression ,Article ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Risk Factors ,030202 anesthesiology ,Humans ,Medicine ,Postoperative Period ,Child ,business.industry ,Incidence ,Mental Disorders ,Incidence (epidemiology) ,Opioid use ,Age Factors ,Chronic pain ,Infant ,Perioperative ,Surgical procedures ,Opioid-Related Disorders ,medicine.disease ,Analgesics, Opioid ,Anesthesiology and Pain Medicine ,Mood ,Prescription opioid ,Child, Preschool ,Surgical Procedures, Operative ,Female ,business ,030217 neurology & neurosurgery - Abstract
BACKGROUND: Long-term opioid use has negative healthcare consequences. Opioid-naïve adults are at risk for prolonged and persistent opioid use after surgery. While these outcomes have been examined in some adolescent and teenage populations little is known about the risk of prolonged and persistent postoperative opioid use after common surgeries compared to children who do not undergo surgery, and factors associated with these issues among pediatric surgical patients of all ages. METHODS: Using a national administrative claims database, we identified 175,878 surgical visits by opioid-naïve children aged ≤18 who underwent ≥1 of the 20 most common surgeries from each of four age groups between December 31, 2002 and December 30, 2017, and who filled a perioperative opioid prescription 30 days before to 14 days after surgery. Prolonged opioid use after surgery (filling ≥1 opioid prescription 90–180 days after surgery) was compared to a reference sample of 1,354,909 nonsurgical patients randomly assigned a false “surgery” date. Multivariable logistic regression models were used to estimate the association of surgical procedures and 22 other variables of interest with prolonged opioid use and persistent postoperative opioid use (filling ≥60 days’ supply of opioids 90–365 days after surgery) for each age group. RESULTS: Prolonged opioid use after surgery occurred in 0.77%, 0.76%, 1.0%, and 3.8% of surgical patients ages 0–
- Published
- 2020
- Full Text
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3. Programmed Intermittent Bolus Regimen for Erector Spinae Plane Blocks in Children
- Author
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Ellen Wang, Farrukh Munshey, Ban C. H. Tsui, and Thomas J Caruso
- Subjects
Male ,Time Factors ,Adolescent ,medicine.drug_class ,Loading dose ,California ,Drug Administration Schedule ,03 medical and health sciences ,0302 clinical medicine ,Bolus (medicine) ,030202 anesthesiology ,Interquartile range ,Humans ,Medicine ,Dosing ,Anesthetics, Local ,Child ,Pain Measurement ,Retrospective Studies ,Pain, Postoperative ,business.industry ,Local anesthetic ,Ropivacaine ,Age Factors ,Nerve Block ,Perioperative ,Analgesics, Opioid ,Regimen ,Treatment Outcome ,Anesthesiology and Pain Medicine ,Child, Preschool ,Anesthesia ,Female ,business ,030217 neurology & neurosurgery ,medicine.drug - Abstract
With few published reports on erector spinae plane block use in children, limited guidance on perioperative local anesthetic dosing exists. We present a series of 22 patients who received erector spinae plane catheters with programmed intermittent bolus for various surgeries. Median loading dose of 0.4 mL/kg (interquartile range [IQR], 0.1 mL/kg) ropivacaine 0.5%, intraoperative bolus of 0.3 mL/kg/h (IQR, 0.1 mL/kg) ropivacaine 0.2%, and a postoperative programmed intermittent bolus regimen of maximum 0.6 mg/kg/h resulted in highest pain scores on postoperative day 1 with a median score of 1.7 of 10 (IQR, 1.8) and highest morphine equivalents consumed on postoperative day 2 with a median score of 0.16 mg/kg up to 120 hours after surgery.
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- 2020
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- View/download PDF
4. Association Between Race and Ethnicity in the Delivery of Regional Anesthesia for Pediatric Patients: A Single-Center Study of 3189 Regional Anesthetics in 25,664 Surgeries
- Author
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Michael R. King, T. Anthony Anderson, Elizabeth De Souza, Julia M. Rosenbloom, and Ellen Wang
- Subjects
Male ,medicine.medical_specialty ,Minority group ,Adolescent ,Ethnic group ,Article ,Cohort Studies ,Health care ,Ethnicity ,Humans ,Medicine ,Healthcare Disparities ,Child ,Retrospective Studies ,Academic Medical Centers ,business.industry ,Racial Groups ,Infant, Newborn ,Infant ,Retrospective cohort study ,Odds ratio ,Confidence interval ,Anesthesiology and Pain Medicine ,Child, Preschool ,Emergency medicine ,Female ,business ,Pediatric anesthesia ,Delivery of Health Care ,Anesthesia, Local ,Cohort study - Abstract
Background Racial and ethnic disparities in health care are well documented in the United States, although evidence of disparities in pediatric anesthesia is limited. We sought to determine whether there is an association between race and ethnicity and the use of intraoperative regional anesthesia at a single academic children's hospital. Methods We performed a retrospective review of all anesthetics at an academic tertiary children's hospital between May 4, 2014, and May 31, 2018. The primary outcome was delivery of regional anesthesia, defined as a neuraxial or peripheral nerve block. The association between patient race and ethnicity (white non-Hispanic or minority) and receipt of regional anesthesia was assessed using multivariable logistic regression. Sensitivity analyses were performed comparing white non-Hispanic to an expansion of the single minority group to individual racial and ethnic groups and on patients undergoing surgeries most likely to receive regional anesthesia (orthopedic and urology patients). Results Of 33,713 patient cases eligible for inclusion, 25,664 met criteria for analysis. Three-thousand one-hundred eighty-nine patients (12.4%) received regional anesthesia. One thousand eighty-six of 8884 (13.3%) white non-Hispanic patients and 2003 of 16,780 (11.9%) minority patients received regional anesthesia. After multivariable adjustment for confounding, race and ethnicity were not found to be significantly associated with receiving intraoperative regional anesthesia (adjusted odds ratios [ORs] = 0.95; 95% confidence interval [CI], 0.86-1.06; P = .36). Sensitivity analyses did not find significant differences between the white non-Hispanic group and individual races and ethnicities, nor did they find significant differences when analyzing only orthopedic and urology patients, despite observing some meaningful clinical differences. Conclusions In an analysis of patients undergoing surgical anesthesia at a single academic children's hospital, race and ethnicity were not significantly associated with the adjusted ORs of receiving intraoperative regional anesthesia. This finding contrasts with much of the existing health care disparities literature and warrants further study with additional datasets to understand the mechanisms involved.
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- 2019
- Full Text
- View/download PDF
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