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In this study, in 2011-2012, single-port thoracoscopic sympathectomy applied 43 patients suffering from hyperhidrosis (excessive sweating) were monitored in the chest surgery clinics of Harran University Hospital and private OSM Hospital Sympathectomy applied locations of the patients, complications and 3-month follow-up were evaluated retrospectively. Single-port thoracoscopy and bilateral sympathectomy was performed on the forty-three patients in the same session. None of the operations was required thoracotomy. All the patients were followed up 3 months. The current status of the complications, sweating recurrance and satisfaction in post operative period were evaluated three months after the operation. After the Single-port thoracoscopic sympathectomy application on the 43 patients, It was observed reflex sweating in 19 patients (44%) , pneumothorax in 4 patients and sweating recurrance in 2 patients (4%) . After 3 months of postoperative monitoring period, it was observed the decrease of reflexive sweating in 5 patients and dissatisfaction and regret were detected only in 2 patients. In our study, it is suggested that the single- port thoracoscopic sympathectomy may be the better option in the treatment of hyperhidrosis. [ABSTRACT FROM AUTHOR]