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Your search keyword '"Zhang, Youyu"' showing total 18 results
Start Over Author "Zhang, Youyu" Journal analytical methods
18 results on '"Zhang, Youyu"'

16. A new turn-on fluorescent sensor based on NBD for highly selective detection of Hg2+in aqueous media and imaging in live cellsElectronic supplementary information (ESI) available. See DOI: 10.1039/c4ay00729h

Author

Shen, Youming, Zhang, Youyu, Zhang, Xiangyang, Zhang, Chunxiang, Zhang, Linli, Jin, Junling, Li, Haitao, and Yao, Shouzhuo

Abstract

A new and simple fluorescent probe bearing 7-nitrobenz-2-oxa-1,3-diazole and N,N-bis(thiophen-2-ylmethyl)ethane-1,2-diamine was developed as a fluorescent chemosensor with high selectivity and sensitivity toward Hg2+over other cations tested. The signaling is due to the coordination of S and N atoms of N,N-bis(thiophen-2-ylmethyl)ethane-1,2-diamine to Hg2+. Upon addition of 30 equivalents of Hg2+, a 45-fold increase in fluorescence emission intensity was observed. Moreover, the probe is further successfully used to image Hg2+in MCF-7 cells.

Published
2014
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17. Label-free DNA sensor for Pb2+based on a duplex–quadruplex exchange

Author

Zhang, Lingli, Mi, Naxiu, Zhang, Youyu, Wei, Mingjie, Li, Haitao, and Yao, Shouzhuo

Abstract

A simple label-free Pb2+fluorescent aptasensor was proposed in this work. It is known that SYBR Green1 can embed into double-stranded DNA resulting in fluorescence enhancement, but it cannot bind to the G-quadruplex formed by Pb2+and PS2.M. In the absence of Pb2+, SYBR Green1 intercalated into the double-stranded DNA hybridized between PS2.M and its complementary strand and the fluorescence was greatly enhanced. In the presence of Pb2+, a compact G-quadruplex structure was formed and the double-stranded structure was destroyed, releasing SYBR Green1 and causing the fluorescence intensity to significantly decrease. The detection limit of the sensor was as low as 3 nM. This proposed assay strategy was a low-cost detection method for Pb2+with high sensitivity and good selectivity.

Published
2013
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18. Fluorescence resonance energy transfer aptasensor for platelet-derived growth factor detection based on upconversion nanoparticles in 30% blood serumElectronic supplementary information (ESI) available. See DOI: 10.1039/c2ay25519g

Author

Lin, Fanbo, Yin, Bangda, li, Chengzhi, Deng, Jianhui, Fan, Xiaoyu, Yi, Yinhui, Liu, Chang, Li, Haitao, Zhang, Youyu, and Yao, Shouzhuo

Abstract

Au nanoparticles (AuNPs) have good absorption properties in the visible region, while upconversion nanoparticles (UCNPs) have an emission at 547 nm upon excitation with a 980 nm laser, which could avoid most interfering signals of biomolecules in serum. In this paper, we developed an aptasensor for platelet-derived growth factor (PDGF–BB) detection in 30% blood serum based on fluorescence resonance energy transfer between AuNPs and UCNPs. With the proposed aptasensor, PDGF–BB in 30% blood serum was detected. Two consecutive linear ranges allow a wide determination of PDGF–BB concentrations with a low detection limit of 10 nM (S/N= 3). Importantly, the fluorescence biosensor can directly detect PDGF–BB in blood serum of lymphoma patient. This detection approach can also exhibit good stability and selectivity.

Published
2013
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