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1. Quantitative analysis by microchip capillary electrophoresis – current limitations and problem-solving strategies

Author

Jens Künnemeyer, Tobias Revermann, Uwe Karst, Sebastian Götz, and Faculty of Science and Technology

Subjects
endocrine system, Chromatography, Capillary electrophoresis, Chemistry, Electrochemistry, Environmental Chemistry, IR-76300, Current (fluid), Biological system, Biochemistry, Quantitative analysis (chemistry), Spectroscopy, Analytical Chemistry
Abstract

Obstacles and possible solutions for the application of microchip capillary electrophoresis in quantitative analysis are described and critically discussed. Differences between the phenomena occurring during conventional capillary electrophoresis and microchip-based capillary electrophoresis are pointed out, with particular focus on electrolysis, bubble formation, clogging, surface interactions, injection and aspects related to the power supply. Current drawbacks are specified and improvements for successful quantitative microchip capillary electrophoresis are suggested.

Published
2008
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2. Quantitative analysis by microchip capillary electrophoresis – current limitations and problem-solving strategies.

Author

Tobias Revermann, Sebastian Götz, Jens Künnemeyer, and Uwe Karst

Subjects
*PHASE partition, *GEL electrophoresis, *ELECTROPHORESIS, *ELECTROCHEMISTRY
Abstract

Obstacles and possible solutions for the application of microchip capillary electrophoresis in quantitative analysis are described and critically discussed. Differences between the phenomena occurring during conventional capillary electrophoresis and microchip-based capillary electrophoresis are pointed out, with particular focus on electrolysis, bubble formation, clogging, surface interactions, injection and aspects related to the power supply. Current drawbacks are specified and improvements for successful quantitative microchip capillary electrophoresis are suggested. [ABSTRACT FROM AUTHOR]

Published
2008
Full Text
View/download PDF

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