1. [Paraneoplastic limbic encephalitis and lung cancer].
- Author
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Gil Ortega M, Hernández Pardo E, Gil Ortega I, Gil Ortega D, Quesada Córcoles J, Gutiérrez Lara G, and Fernández Reyes JL
- Subjects
- Autoantibodies analysis, Carcinoma, Small Cell pathology, Carcinoma, Small Cell therapy, Fatal Outcome, Humans, Limbic Encephalitis diagnosis, Limbic Encephalitis therapy, Lung Neoplasms pathology, Lung Neoplasms therapy, Male, Middle Aged, Seizures diagnosis, Seizures etiology, Seizures therapy, Carcinoma, Small Cell complications, Limbic Encephalitis complications, Lung Neoplasms complications
- Abstract
Paraneoplastic limbic encephalitis (PLE) is a disorder characterized by severe cognitive dysfunction and seizures. It is usually associated with small cell lung carcinoma. Diagnosis is difficult because clinical markers are often lacking, and symptoms usually precede the diagnosis of cancer. Serological detection of antineuronal antibodies can be useful. We describe a patient with symptoms of limbic encephalitis, negative for paraneoplastic antibodies, in whom lung cancer was detected.
- Published
- 2004
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